Evidence map›Paper›PMID 36729297›Full record

ArticleApplied biochemistry and biotechnology2023

The Dual Therapeutic Potential of Ottelione A on Carbon Tetrachloride-induced Hepatic Toxicity in Mice.

Rasha Fekry Zahran, Lina Mahmoud El-Sayed, Thomas Robert Hoye, Seif-Eldin Nasr Ayyad

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied biochemistry and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Rasha Fekry ZahranBiochemistry division, Chemistry Department, Faculty of Science, Damietta University, 34517, Damietta, New-Damietta, Egypt. zahran@du.edu.eg.ORCID http://orcid.org/0000-0001-9530-1751
Lina Mahmoud El-SayedBiochemistry division, Chemistry Department, Faculty of Science, Damietta University, 34517, Damietta, New-Damietta, Egypt.
Thomas Robert HoyeDepartments of Chemistry and Medicinal Chemistry, University of Minnesota, 55455, Minneapolis, MN, USA.
Seif-Eldin Nasr AyyadDepartment of Chemistry, Faculty of Science, Damietta University, New Damietta, Egypt.
Damietta University · EGUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome herbal natural products play an important role in protecting organisms from the toxic effect of some xenobiotics. The present study was designed to evaluate the potential therapeutic effects of Ottelione A (OTTE) against carbon tetrachloride(CCl

methodsAdult male Swiss albino mice were divided into six groups: group I was used as a normal control received olive oil; group II received DMSO; group III received OTTE; group IV received CCl

resultsOur results showed that the administration of CCl

conclusionOttelione A (OTTE) has good antioxidant and therapeutic properties, which can help in preventing CCl

Indexed as

Carbon TetrachlorideChemical and Drug Induced Liver InjuryAnimalsAntioxidantsCyclohexanonesLiverMaleMiceOlive OilOxidative StressPlant ExtractsAntioxidantsCarbon TetrachlorideCyclohexanonesOlive Oilottelione APlant ExtractsCCl4Hepato-protectiveHepatoxicityOttelia allismoideOxidative stressTGFß1

Identifiers

PMID36729297
PMCPMC10511377
OpenAlexW4318921226

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.