Evidence map›Paper›PMID 36729174›Full record

ArticleEuropean radiology2023

Radiation dose optimization for photon-counting CT coronary artery calcium scoring for different patient sizes: a dynamic phantom study.

Magdalena M Dobrolinska, Niels R van der Werf, Judith van der Bie, Joël de Groen, Marcel Dijkshoorn, Ronald Booij, Ricardo P J Budde, Marcel J W Greuter, Marcel van Straten

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Trading off Iodine and Radiation Dose in Coronary Computed Tomography.Journal of cardiovascular development and disease · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Journal of medical imaging (Bellingham, Wash.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Magdalena M Dobrolinska *Department of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Niels R van der Werf *Department of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands. nrvdwerf@gmail.com.
Judith van der BieDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Joël de GroenDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Marcel DijkshoornDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Ronald BooijDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Ricardo P J BuddeDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Marcel J W GreuterDepartment of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Marcel van StratenDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Erasmus MC · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo systematically assess the radiation dose reduction potential of coronary artery calcium (CAC) assessments with photon-counting computed tomography (PCCT) by changing the tube potential for different patient sizes with a dynamic phantom.

methodsA hollow artery, containing three calcifications of different densities, was translated at velocities corresponding to 0, < 60, 60-75, and > 75 beats per minute within an anthropomorphic phantom. Extension rings were used to simulate average- and large -sized patients. PCCT scans were made with the reference clinical protocol (tube potential of 120 kilovolt (kV)), and with 70, 90, Sn100, Sn140, and 140 kV at identical image quality levels. All acquisitions were reconstructed at a virtual monoenergetic energy level of 70 keV. For each calcification, Agatston scores and contrast-to-noise ratios (CNR) were determined, and compared to the reference with Wilcoxon signed-rank tests, with p < 0.05 indicating significant differences.

resultsA decrease in radiation dose (22%) was achieved at Sn100 kV for the average-sized phantom. For the large phantom, Sn100 and Sn140 kV resulted in a decrease in radiation doses of 19% and 3%, respectively. Irrespective of CAC density, Sn100 and 140 kVp did not result in significantly different CNR. Only at Sn100 kV were there no significant differences in Agatston scores for all CAC densities, heart rates, and phantom sizes.

conclusionPCCT at tube voltage of 100 kV with added tin filtration and reconstructed at 70 keV enables a ≥ 19% dose reduction compared to 120 kV, independent of phantom size, CAC density, and heart rate. KEY POINTS: • Photon-counting CT allows for reduced radiation dose acquisitions (up to 19%) for coronary calcium assessment by reducing tube voltage while reconstructing at a normal monoE level of 70 keV. • Tube voltage reduction is possible for medium and large patient sizes, without affecting the Agatston score outcome.

Indexed as

CalcinosisCalciumCoronary VesselsHumansPhantoms, ImagingRadiation DosageTomography, X-Ray ComputedCalciumCalciumCoronary vesselsImaging phantomsX-ray computed tomography

Identifiers

PMID36729174
PMCPMC10290002
OpenAlexW4318932695

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.