Evidence map›Paper›PMID 36728713›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Discovery of novel 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives as multifunctional MAO-B inhibitors for the treatment of Parkinson's disease.

Zhongcheng Cao, Xingyue Wang, Tianlong Zhang, Xianwu Fu, Fan Zhang, Jiang Zhu

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Organosulfur Compounds: Potential Therapeutics for Parkinson's Disease.CNS & neurological disorders drug targets · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhongcheng CaoSchool of Pharmacy, North Sichuan Medical College, Nanchong, China.
Xingyue WangSchool of Pharmacy, North Sichuan Medical College, Nanchong, China.
Tianlong ZhangSchool of Pharmacy, North Sichuan Medical College, Nanchong, China.
Xianwu FuSchool of Pharmacy, North Sichuan Medical College, Nanchong, China.
Fan ZhangSchool of Pharmacy, North Sichuan Medical College, Nanchong, China.
Jiang ZhuSichuan Key Laboratory of Medical Imaging, School of Pharmacy and Nanchong Key Laboratory of MRI Contrast Agent, North Sichuan Medical College, Nanchong, China.
North Sichuan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To discover novel multifunctional agents for the treatment of Parkinson's disease, a series of 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives was designed, synthesized and evaluated. The results revealed that representative compound

Indexed as

Neuroprotective AgentsParkinson DiseaseBenzothiazolesHumansHydroxyl RadicalMolecular StructureMonoamine OxidaseMonoamine Oxidase InhibitorsStructure-Activity RelationshipBenzothiazolesHydroxyl RadicalMonoamine OxidaseMonoamine Oxidase InhibitorsNeuroprotective Agents2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivativesanti-neuroinflammatory agentsMAO-B inhibitorsmultifunctional anti-PD agentsParkinson’s disease

Identifiers

PMID36728713
PMCPMC9897792
OpenAlexW4318911797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.