Evidence map›Paper›PMID 36728456›Full record

ArticlemSphere2023

Metagenomic Analysis of the Abundance and Composition of Antibiotic Resistance Genes in Hospital Wastewater in Benin, Burkina Faso, and Finland.

Melina A Markkanen, Kaisa Haukka, Katariina M M Pärnänen, Victorien Tamegnon Dougnon, Isidore Juste O Bonkoungou, Zakaria Garba, Halidou Tinto, Anniina Sarekoski, Antti Karkman, Anu Kantele and 1 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Melina A MarkkanenDepartment of Microbiology, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-2392-1729
Kaisa HaukkaDepartment of Microbiology, University of Helsinki, Helsinki, Finland.
Katariina M M PärnänenDepartment of Microbiology, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-2220-1738
Victorien Tamegnon DougnonResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, Benin.
Isidore Juste O BonkoungouDepartment of Biochemistry and Microbiology, University Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.
Zakaria GarbaClinical Research Unit Nanoro, Institute for Research in Health Sciences, National Center for Scientific and Technological Research, Ouagadougou, Burkina Faso.
Halidou TintoClinical Research Unit Nanoro, Institute for Research in Health Sciences, National Center for Scientific and Technological Research, Ouagadougou, Burkina Faso.
Anniina SarekoskiDepartment of Microbiology, University of Helsinki, Helsinki, Finland.
Antti KarkmanDepartment of Microbiology, University of Helsinki, Helsinki, Finland.ORCID 0000-0003-0983-3319
Anu Kantele *Multidisciplinary Center of Excellence in Antimicrobial Resistance Research, University of Helsinki, Helsinki, Finland.
Marko P J Virta *Department of Microbiology, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-5981-7566
University of Helsinki · FICentre National de la Recherche Scientifique et Technologique · BFUniversité d'Abomey-Calavi · BJUniversité Joseph Ki-Zerbo · BF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance is a global threat to human health, with the most severe effect in low- and middle-income countries. We explored the presence of antibiotic resistance genes (ARGs) in the hospital wastewater (HWW) of nine hospitals in Benin and Burkina Faso, two low-income countries in West Africa, with shotgun metagenomic sequencing. For comparison, we also studied six hospitals in Finland. The highest sum of the relative abundance of ARGs in the 68 HWW samples was detected in Benin and the lowest in Finland. HWW resistomes and mobilomes in Benin and Burkina Faso resembled each other more than those in Finland. Many carbapenemase genes were detected at various abundances, especially in HWW from Burkina Faso and Finland. The

Indexed as

Anti-Bacterial AgentsWastewaterBeninBurkina FasoDrug Resistance, MicrobialFinlandHospitalsHumansAnti-Bacterial AgentsWastewaterantibiotic resistancecarbapenemasecolistin resistancehospital wastewater (HWW)metagenomesWest Africa

Identifiers

PMID36728456
PMCPMC9942590
OpenAlexW4318925423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.