Evidence map›Paper›PMID 36727824›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Dual-Cascade Activatable Nanopotentiators Reshaping Adenosine Metabolism for Sono-Chemodynamic-Immunotherapy of Deep Tumors.

Meixiao Zhan, Fengshuo Wang, Yao Liu, Jianhui Zhou, Wei Zhao, Ligong Lu, Jingchao Li, Xu He

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 101 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Hollow RuOTheranostics · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Engineering Stimuli-Responsive Materials for Precision Medicine.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Meixiao ZhanGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Jinan University, Zhuhai, Guangdong, 519000, China.
Fengshuo WangState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620, China.
Yao LiuGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Jinan University, Zhuhai, Guangdong, 519000, China.
Jianhui ZhouState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620, China.
Wei ZhaoGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Jinan University, Zhuhai, Guangdong, 519000, China.
Ligong LuGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Jinan University, Zhuhai, Guangdong, 519000, China.
Jingchao LiState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Biological Science and Medical Engineering, Donghua University, Shanghai, 201620, China.ORCID 0000-0002-8994-3202
Xu HeGuangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai People's Hospital (Zhuhai hospital affiliated with Jinan University), Jinan University, Zhuhai, Guangdong, 519000, China.
Jinan University · CNDonghua University · CN

Funding

Foundation of Department of Science and Technology of Sichuan Province 2020YFQ0004Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment 2021B1212040004National Natural Science Foundation of China 81903165National Natural Science Foundation of China 82001934National Natural Science Foundation of China 82230067National Natural Science Foundation of China 82272103Natural Science Foundation of Guangdong Province of China 2022B1515020010
6 · The paper itself

Abstract

Immunotherapy is an attractive treatment strategy for cancer, while its efficiency and safety need to be improved. A dual-cascade activatable nanopotentiator for sonodynamic therapy (SDT) and chemodynamic therapy (CDT)-cooperated immunotherapy of deep tumors via reshaping adenosine metabolism is herein reported. This nanopotentiator (NP

Indexed as

Manganese CompoundsOxidesAdenosineImmunotherapyReactive Oxygen SpeciesAdenosineManganese CompoundsOxidesReactive Oxygen Speciesadenosine metabolismcancer therapydeep tumorsimmunotherapynanopotentiators

Identifiers

PMID36727824
PMCPMC10074132
OpenAlexW4318931856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.