Evidence map›Paper›PMID 36727657›Full record

ArticleMolecular carcinogenesis2023

Systemic deuteration of SCID mice using the water-isotopologue deuterium oxide (D

Jana Jandova, Jean-Philippe Galons, David L Dettman, Georg T Wondrak

Open access · hybridAbstract read
In one paragraph

Article in Molecular carcinogenesis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Deuterated water (Frontiers in immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jana JandovaDepartment of Pharmacology and Toxicology, R. Ken Coit College of Pharmacy & UA Cancer Center, The University of Arizona, Tucson, Arizona, USA.
Jean-Philippe GalonsDepartment of Medical Imaging, The University of Arizona, Tucson, Arizona, USA.
David L DettmanDepartment of Geosciences, The University of Arizona, Tucson, Arizona, USA.
Georg T WondrakDepartment of Pharmacology and Toxicology, R. Ken Coit College of Pharmacy & UA Cancer Center, The University of Arizona, Tucson, Arizona, USA.
University of Arizona · USBanner - University Medical Center Tucson · US

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI George S Watts · 1994 to 2026
$36.7M
Training in Environmental Toxicology of Human DiseaseT32ES007091 · NIEHS · UNIVERSITY OF ARIZONA · PI Nathan J Cherrington · 1985 to 2026
$10.7M
Targeted Prevention for Non-Melanoma Skin CancerP01CA229112 · NCI · UNIVERSITY OF ARIZONA · PI MANSOUR, HEIDI M. · 2019 to 2023
$7.1M
Repurposing Clinical ACT Antimalarials for Experimental Melanoma InterventionR01CA229418 · NCI · UNIVERSITY OF ARIZONA · PI WONDRAK, GEORG T · 2019 to 2023
$1.7M
Bruker Biospec 7T Small Animal MRI UpgradeS10OD025016 · OD · UNIVERSITY OF ARIZONA · PI TROUARD, THEODORE P · 2018 to 2018
$600k
MAGNEX MODEL MRBR 7T/201 AS SHIELDED MAGNET SYSTEM: METABOLISMS10RR021180 · NCRR · UNIVERSITY OF ARIZONA · PI GALONS, JEAN-PHILIPPE · 2005 to 2005
$500k
Exploring the role of HOCI in skin photodamage, immunosuppression, and carcinogenesisR21ES029579 · NIEHS · UNIVERSITY OF ARIZONA · PI WONDRAK, GEORG T · 2019 to 2020
$409k
NCI NIH HHS P01 CA229112NCI NIH HHS P30 CA023074NCI NIH HHS R01 CA229418NCRR NIH HHS S10 RR021180NIEHS NIH HHS P30 ES006694NIEHS NIH HHS R21 ES029579NIEHS NIH HHS T32 ES007091NIH HHSNIH HHS S10 OD025016
6 · The paper itself

Abstract

Since its initial discovery as a natural isotopologue of dihydrogen oxide (

Indexed as

Carcinoma, Pancreatic DuctalDrinking WaterPancreatic NeoplasmsAnimalsApoptosisCell Line, TumorCell ProliferationCore Binding Factor Alpha 2 SubunitDeuterium OxideHumansMiceMice, SCIDCore Binding Factor Alpha 2 SubunitDeuterium OxideDrinking Waterbioluminescent orthotopic xenograftBxPC-3-luciferase reporter celldeuterium oxideendoplasmic reticulum stress responsehuman pancreatic ductal adenocarcinoma

Identifiers

PMID36727657
PMCPMC10106369
OpenAlexW4318919106

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.