Evidence map›Paper›PMID 36727630›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023

Temporal longitudinal associations of carotid-femoral pulse wave velocity and carotid intima-media thickness with resting heart rate and inflammation in youth.

Andrew O Agbaje, Samuel Barmi, Kate M Sansum, Tracy Baynard, Alan R Barker, Tomi-Pekka Tuomainen

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Hypertension in middle childhood.BMC pediatrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Andrew O AgbajeInstitute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland.ORCID 0000-0001-5138-3441
Samuel BarmiInstitute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland.
Kate M SansumChildren's Health and Exercise Research Centre, Sport and Health Sciences, University of Exeter, Exeter, United Kingdom.
Tracy BaynardIntegrative Physiology Laboratory, Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, United States.ORCID 0000-0002-5150-4095
Alan R BarkerChildren's Health and Exercise Research Centre, Sport and Health Sciences, University of Exeter, Exeter, United Kingdom.ORCID 0000-0001-8610-5417
Tomi-Pekka TuomainenInstitute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland.
University of Eastern Finland · FIUniversity of British Columbia · CAUniversity of Exeter · GBUniversity of Illinois Chicago · US

Funding

British Heart Foundation CS/15/6/31468Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MR/L010305/1Medical Research Council MR/M006727/1Wellcome Trust
6 · The paper itself

Abstract

We examined the temporal longitudinal associations of carotid-femoral pulse wave velocity (cfPWV) and carotid intima-media thickness (cIMT) with the risk of elevated resting heart rate (RHR) and high-sensitivity C-reactive protein (hsCRP). We studied 3,862 adolescents, mean age 17.7 (SD 0.3 yr), followed-up for 7 yr until age 24.5 (0.7) yr, from the Avon Longitudinal Study of Parents and Children, UK. RHR, fasting plasma hsCRP, cfPWV, and cIMT were repeatedly assessed and analyzed using logistic regression, linear mixed-effect, and structural equation models adjusting for important covariates. Among 3,862 adolescents [2,143 (55.5%) female], 10% and 44% were at moderate-to-high risk of elevated RHR and hsCRP at 24.5 yr, respectively. Higher cfPWV at 17.7 yr was associated with elevated RHR risk at follow-up [odds-ratio (OR) 1.58 (CI 1.20-2.08);

Indexed as

Carotid Intima-Media ThicknessVascular StiffnessAdolescentAdultCarotid-Femoral Pulse Wave VelocityChildC-Reactive ProteinFemaleHeart RateHumansInflammationLongitudinal StudiesMalePulse Wave AnalysisRisk FactorsYoung AdultC-Reactive Proteinatherosclerosisbirth cohortcarotid-femoral pulse wave velocitycausal inferencehigh-sensitivity C reactive protein

Identifiers

PMID36727630
PMCPMC10010920
OpenAlexW4318920672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.