Evidence map›Paper›PMID 36726970›Full record

ArticleFrontiers in immunology2022

Lack of seroresponse to SARS-CoV-2 booster vaccines given early post-transplant in patients primed pre-transplantation.

Sarah Gleeson, Paul Martin, Tina Thomson, Katrina J Spensley, Dawn Goodall, Rachna Bedi, Amarpreet Kaur Thind, Charlotte Seneschall, Jaslyn Gan, Stephen McAdoo and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Sarah GleesonCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Paul MartinCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Tina ThomsonImperial College Renal and Transplant Centre, Imperial College Healthcare National Healthcare Service Trust, Hammersmith Hospital, London, United Kingdom.
Katrina J SpensleyCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Dawn GoodallImperial College Renal and Transplant Centre, Imperial College Healthcare National Healthcare Service Trust, Hammersmith Hospital, London, United Kingdom.
Rachna BediImperial College Renal and Transplant Centre, Imperial College Healthcare National Healthcare Service Trust, Hammersmith Hospital, London, United Kingdom.
Amarpreet Kaur ThindCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Charlotte SeneschallImperial College Renal and Transplant Centre, Imperial College Healthcare National Healthcare Service Trust, Hammersmith Hospital, London, United Kingdom.
Jaslyn GanImperial College Renal and Transplant Centre, Imperial College Healthcare National Healthcare Service Trust, Hammersmith Hospital, London, United Kingdom.
Stephen McAdooCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Liz LightstoneCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Peter KelleherDepartment of Infection and Immunity Sciences Northwest London Pathology NHS Trust, Charing Cross Hospital, London, United Kingdom.
Maria PrendeckiCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Michelle WillicombeCentre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Hammersmith Hospital · GBImperial College Healthcare NHS Trust · GBImperial College London · GBCharing Cross Hospital · GB

Funding

Department of Health
6 · The paper itself

Abstract

SARS-CoV-2 vaccines are recommended pre-transplantation, however, waning immunity and evolving variants mandate booster doses. Currently there no data to inform the optimal timing of booster doses post-transplant, in patients primed pre-transplant. We investigated serial serological samples in 204 transplant recipients who received 2 or 3 SARS-CoV-2 vaccines pre-transplant. Spike protein antibody concentrations, [anti-S], were measured on the day of transplantation and following booster doses post-transplant. In infection-naïve patients, post-booster [anti-S] did not change when V3 (1

Indexed as

COVID-19TransplantsAntibodiesCOVID-19 VaccinesHumansSARS-CoV-2Transplant RecipientsAntibodiesCOVID-19 VaccinesCOVID- 19immunosuppressedinfectionkidney transplantSARS-CoV-2vaccine

Identifiers

PMID36726970
PMCPMC9885043
OpenAlexW4316363123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.