Evidence map›Paper›PMID 36726844›Full record

ReviewBioMed research international2023

Recent Approaches for Downplaying Antibiotic Resistance: Molecular Mechanisms.

Sarfraz Ahmed, Muhammad Zeeshan Ahmed, Safa Rafique, Seham Eid Almasoudi, Mohibullah Shah, Nur Asyilla Che Jalil, Suvash Chandra Ojha

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Article
  3. Mechanisms ofMedicina (Kaunas, Lithuania) · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Menadione as Antibiotic Adjuvant AgainstAntibiotics (Basel, Switzerland) · 2025
    Article
  11. Therapeutic efficacy ofFrontiers in nutrition · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Characterization of a Novel Sequence Type (ST) 6758Infection and drug resistance · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Antibiotic adjuvants: synergistic tool to combat multi-drug resistant pathogens.Frontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 4 countries.

Sarfraz AhmedDepartment of Basic Sciences, University of Veterinary and Animal Sciences Lahore, Narowal Campus, 51600 Narowal, Pakistan.ORCID https://orcid.org/0000-0001-5879-0461
Muhammad Zeeshan AhmedDepartment of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.ORCID https://orcid.org/0000-0003-1118-3693
Safa RafiqueSchool of Biochemistry and Biotechnology, University of the Punjab, 54590 Lahore, Pakistan.
Seham Eid AlmasoudiUniversity of Tabuk, King Faisal Street, 47512 Tabuk, Saudi Arabia.
Mohibullah ShahDepartment of Biochemistry, Bahauddin Zakariya University, Multan 60800, Pakistan.
Nur Asyilla Che JalilDepartment of Pathology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.ORCID https://orcid.org/0000-0001-5871-2295
Suvash Chandra OjhaDepartment of Infectious Diseases, The Affiliated Hospital of Southwest Medical University, 646000 Luzhou, China.ORCID https://orcid.org/0000-0003-1289-2985
Bahauddin Zakariya University · PKAffiliated Hospital of Southwest Medical University · CNUniversiti Sains Malaysia · MYUniversity of Tabuk · SAUniversity of the Punjab · PKUniversity of Veterinary and Animal Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a ubiquitous public health menace. AMR emergence causes complications in treating infections contributing to an upsurge in the mortality rate. The epidemic of AMR in sync with a high utilization rate of antimicrobial drugs signifies an alarming situation for the fleet recovery of both animals and humans. The emergence of resistant species calls for new treatments and therapeutics. Current records propose that health drug dependency, veterinary medicine, agricultural application, and vaccination reluctance are the primary etymology of AMR gene emergence and spread. Recently, several encouraging avenues have been presented to contest resistance, such as antivirulent therapy, passive immunization, antimicrobial peptides, vaccines, phage therapy, and botanical and liposomal nanoparticles. Most of these therapies are used as cutting-edge methodologies to downplay antibacterial drugs to subdue the resistance pressure, which is a featured motive of discussion in this review article. AMR can fade away through the potential use of current cutting-edge therapeutics, advancement in antimicrobial susceptibility testing, new diagnostic testing, prompt clinical response, and probing of new pharmacodynamic properties of antimicrobials. It also needs to promote future research on contemporary methods to maintain host homeostasis after infections caused by AMR. Referable to the microbial ability to break resistance, there is a great ultimatum for using not only appropriate and advanced antimicrobial drugs but also other neoteric diverse cutting-edge therapeutics.

Indexed as

Anti-Infective AgentsVaccinesAnimalsAnti-Bacterial AgentsDrug Resistance, BacterialDrug Resistance, MicrobialHumansPublic HealthAnti-Bacterial AgentsAnti-Infective AgentsVaccines

Identifiers

PMID36726844
PMCPMC9886476
OpenAlexW4317815849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.