Evidence map›Paper›PMID 36726811›Full record

ReviewClinical, cosmetic and investigational dermatology2023

The Challenges in Investigating the Pathogenesis of Sensitive Skin by Noninvasive Measurements: A Systematic Review.

Shiyu Yan, Jinfeng Zhao, Yuqing Han, Rui Wang, Kexuan Bai, Junxin Ge, Yao Pan, Hua Zhao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical, cosmetic and investigational dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Skin examination in extreme conditions.Acta biochimica Polonica · 2026
    Review
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shiyu YanDepartment of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.
Jinfeng ZhaoDepartment of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.
Yuqing HanDepartment of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.
Rui WangDepartment of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.
Kexuan BaiDepartment of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.
Junxin GeDepartment of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.
Yao PanDepartment of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.ORCID 0000-0002-8092-4865
Hua ZhaoDepartment of Cosmetics, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, 100048, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sensitive skin (SS) is a common cutaneous condition that seriously affects people's quality of life, but studies of sensitive skin pathogenesis are unclear, the exploration are ongoing, and the biophysical properties of sensitive skin disagree with the study results. In this paper, we summarize the noninvasive biophysical and imaging instrumental methods used for sensitive skin and provide support for the classification of sensitive skin subtypes to prescribe precise treatment. PubMed and Web of Science databases were searched according to PRISMA guidelines for articles from January 1971 to May 2022 that used noninvasive biophysical or imaging methods to monitor adult subjects with sensitive skin. The quality of the included articles was determined based on 22 items of the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) statement. A total of 55 studies were included, representing 8 biophysical and 5 imaging methods and their applications in treatment efficacy evaluation studies. The biophysical parameter and cutaneous morphological property changes in sensitive skin subjects were observed. The quality of the studies was relatively low, and there was high variability in results between studies. Several parameters have shown tremendous potential in exploring the pathogenesis with different sensitive skin subtypes: type I may be detected with higher transepidermal water loss and lower stratum corneum hydration values, as well as with thinner epidermis with a shallower and more irregular honeycomb structure; Type II and III are more prone to higher blood flow, lower current perception threshold than normal skin. This systematic review identifies key reasons for the lack of uniform trends in noninvasive measurements and recommends the use of effective selection instruments or relevant parameters to explore the pathogenesis of sensitive skin, and to differentiate the subtypes of sensitive skin for achieving the precise treatment.

Indexed as

lactic acid sting testreflectance confocal microscopysensitive skinstratum corneum hydrationtransdermal water losstransepidermal water lossVISIA

Identifiers

PMID36726811
PMCPMC9885880

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.