Evidence map›Paper›PMID 36726785›Full record

ArticleFrontiers in pharmacology2022

Comparative metabolism and tolerability of racemic primaquine and its enantiomers in human volunteers during 7-day administration.

Washim Khan, Yan-Hong Wang, Narayan D Chaurasiya, N P Dhammika Nanayakkara, H M Bandara Herath, Kerri A Harrison, Gray Dale, Donald A Stanford, Eric P Dahl, James D McChesney and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Washim KhanNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
Yan-Hong WangNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
Narayan D ChaurasiyaDepartment of Infectious Diseases, Division of Drug Discovery, Southern Research Institute, Birmingham, AL, United States.
N P Dhammika NanayakkaraNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
H M Bandara HerathNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
Kerri A HarrisonNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
Gray DaleNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
Donald A StanfordNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
Eric P DahlNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
James D McChesneyIronstone Separations Inc., Etta, MS, United States.
Waseem GulElSohly Laboratories Inc., Oxford, MS, United States.
Mahmoud A ElSohlyNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
David JollowProfessor Emeritus, Department Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, United States.
Babu L TekwaniDepartment of Infectious Diseases, Division of Drug Discovery, Southern Research Institute, Birmingham, AL, United States.
Larry A WalkerNational Center for Natural Products Research, The University of Mississippi, University, MS, United States.
University of Mississippi · USSouthern Research Institute · USElSohly Laboratories (United States) · USMedical University of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primaquine (PQ) is an 8-aminoquinoline antimalarial, active against dormant

Indexed as

clinical pharmacokineticsenantiomersmetabolismprimaquineracematesafety

Identifiers

PMID36726785
PMCPMC9885159
OpenAlexW4316362857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.