Evidence map›Paper›PMID 36726777›Full record

ArticleBrain communications2023

Vagal cross-sectional area correlates with parasympathetic dysfunction in Parkinson's disease.

Sophie Huckemann, Katharina Mueller, Paulina Averdunk, Eva Kühn, Lovis Hilker, Saskia Kools, Leonard Scholz, Yesim Bulut, Jil Brünger, Sean Fiegert and 8 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Correlation between right vagus nerve cross-sectional area and abnormal heart rate with deep breathing in Parkinson's disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Sophie HuckemannDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Katharina MuellerDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Paulina AverdunkDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Eva KühnDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Lovis HilkerDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Saskia KoolsDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Leonard ScholzDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Yesim BulutDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Jil BrüngerDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Sean FiegertDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Thomas GrüterDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Anna Lena FisseDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Jeremias MotteDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Min-Suk YoonDepartment of Neurology, Augusta Clinic, Hattingen, Germany.
Ralf GoldDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Christiane Schneider-GoldDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Lars TöngesDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.ORCID https://orcid.org/0000-0001-6621-144X
Kalliopi PitarokoiliDepartment of Neurology, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.ORCID https://orcid.org/0000-0002-2483-4929
St. Josef-Hospital · DEAugusta Krankenhaus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this prospective study was to investigate autonomic function in Parkinson's disease with a multidimensional approach including clinical evaluation tools, head-up tilt test and morphological studies of the vagus nerve. Head-up tilt test parameters including high frequency power of the heart frequency interval, the ratio of low frequency power of the distance between two consecutive R waves in electrocardiogram (RR interval) to the high frequency and low frequency power of systolic blood pressure were used to evaluate parasympathetic, cardiac sympathetic and vasomotor sympathetic functions, respectively, in 80 patients with Parkinson's disease. We examined the cross-sectional area of the vagus nerves bilaterally using nerve ultrasound and compared mean values with a control group of healthy subjects (

Indexed as

head-up tilt testhigh resolution nerve ultrasoundnerve conduction studyParkinson’s diseaseperipheral neuropathy

Identifiers

PMID36726777
PMCPMC9883711
OpenAlexW4317215187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.