Evidence map›Paper›PMID 36726728›Full record

ArticlePeerJ2023

Novel genetic variants in long non-coding RNA MEG3 are associated with the risk of asthma.

Kuo-Liang Chiu, Wen-Shin Chang, Chia-Wen Tsai, Mei-Chin Mong, Te-Chun Hsia, Da-Tian Bau

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Kuo-Liang ChiuDivision of Chest Medicine, Department of Internal Medicine, Taichung Tzu Chi Hospital, Taichung, Taiwan.
Wen-Shin ChangGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
Chia-Wen TsaiGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
Mei-Chin MongDepartment of Food Nutrition and Health Biotechnology, Asia University, Taichung, Taiwan.
Te-Chun HsiaTerry Fox Cancer Research Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Da-Tian BauGraduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
China Medical University · TWAsia University · TWChina Medical University Hospital · TWTaichung Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Asthma is the most common chronic inflammatory airway disease worldwide. Asthma is a complex disease whose exact etiologic mechanisms remain elusive; however, it is increasingly evident that genetic factors play essential roles in the development of asthma. The purpose of this study is to identify novel genetic susceptibility loci for asthma in Taiwanese. We selected a well-studied long non-coding RNA (lncRNA), Methods: We genotyped four single nucleotide polymorphisms (SNPs) in Results: The variant AG and AA genotypes of Conclusion:

Indexed as

AsthmaRNA, Long NoncodingGenetic Predisposition to DiseaseGenotypeHumansPolymorphism, Single NucleotideMEG3 non-coding RNA, humanRNA, Long NoncodingAsthmaGenotypeMEG3PolymorphismTranscriptional expression

Identifiers

PMID36726728
PMCPMC9885862
OpenAlexW4318214858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.