Evidence map›Paper›PMID 36726581›Full record

ArticleFrontiers in pharmacology2023

Sex-specific decision-making impairments and striatal dopaminergic changes after binge drinking history in rats.

Pierre Sauton, Jerome Jeanblanc, Farid Benzerouk, Fabien Gierski, Mickael Naassila

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Repeated Cocaine Intake Differentially Impacts Striatal DInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pierre SautonINSERM UMR 1247-Research Group on Alcohol & Pharmacodependences (GRAP), Université de Picardie Jules Verne, Centre Universitaire de Recherche en Santé, Amiens, France.
Jerome JeanblancINSERM UMR 1247-Research Group on Alcohol & Pharmacodependences (GRAP), Université de Picardie Jules Verne, Centre Universitaire de Recherche en Santé, Amiens, France.
Farid BenzeroukINSERM UMR 1247-Research Group on Alcohol & Pharmacodependences (GRAP), Université de Picardie Jules Verne, Centre Universitaire de Recherche en Santé, Amiens, France.
Fabien GierskiINSERM UMR 1247-Research Group on Alcohol & Pharmacodependences (GRAP), Université de Picardie Jules Verne, Centre Universitaire de Recherche en Santé, Amiens, France.
Mickael NaassilaINSERM UMR 1247-Research Group on Alcohol & Pharmacodependences (GRAP), Université de Picardie Jules Verne, Centre Universitaire de Recherche en Santé, Amiens, France.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Binge drinking (BD) is a harmful behavior for health and is a predictive factor for the development of alcohol addiction. Weak decision-making (DM) capacities could play a role in the vulnerability to BD which in turn would lead to DM impairments, thus perpetuating BD. Longitudinal preclinical studies are however lacking and necessary to understand this complex relationship. Both DM and BD are influenced by sex and involve dopamine release in the core of the nucleus accumbens, a central mechanism regulated by dopamine D2/3 autoreceptors. In this context, we used an operant self-administration procedure of BD in male and female rats, and longitudinally assessed DM capacity, memory and anxiety-like behavior. To better understand the mechanisms potentially involved in the relationship between DM and BD,

Indexed as

binge drinkingdecision makingdopaminenucleus accumbens coresex

Identifiers

PMID36726581
PMCPMC9885167
OpenAlexW4316363565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.