Evidence map›Paper›PMID 36726107›Full record

Trial reportBMC public health2023

Investigating the effectiveness of three school based interventions for preventing psychotic experiences over a year period - a secondary data analysis study of a randomized control trial.

Lorna Staines, Colm Healy, Paul Corcoran, Helen Keeley, Helen Coughlan, Elaine McMahon, Padraig Cotter, David Cotter, Ian Kelleher, Camilla Wasserman and 7 more

Erratum issuedOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Integrated care models for youth mental health: A systematic review and meta-analysis.The Australian and New Zealand journal of psychiatry · 2024
    Pooled it
  2. Pooled it
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  6. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 7 countries.

Lorna Staines *Department of Psychiatry, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin, Ireland. lornastaines@rcsi.com.ORCID http://orcid.org/0000-0002-3671-3892
Colm Healy *Department of Psychiatry, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin, Ireland.
Paul CorcoranNational Suicide Research Foundation, Cork, Ireland.
Helen KeeleyChild and Adolescent Mental Health Services North Cork, Health Service Executive, Cork, Ireland.
Helen CoughlanDepartment of Psychiatry, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin, Ireland.
Elaine McMahonNational Suicide Research Foundation, Cork, Ireland.
Padraig CotterResearch Society of Process Oriented Psychology United Kingdom (RSPOPUK), Old Hampstead Townhall 213 Haverstock Hill, NW3 4QP, London, UK.
David CotterDepartment of Psychiatry, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin, Ireland.
Ian KelleherDepartment of Psychiatry, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin, Ireland.
Camilla WassermanDepartment of Child and Adolescent Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA.
Romuald BrunnerClinic for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Regensburg, Regensburg, Germany.
Michael KaessUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.
Marco SarchiaponeDepartment of Medicine and Health Science, University of Molise, Campobasso, Italy.
Christina W HovenDepartment of Child and Adolescent Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA.
Vladimir CarliNational Centre for Suicide Research and Prevention of Mental lll-Health (NASP), Karolinska Institute, Stockholm, Sweden.
Danuta WassermanNational Centre for Suicide Research and Prevention of Mental lll-Health (NASP), Karolinska Institute, Stockholm, Sweden.
Mary CannonDepartment of Psychiatry, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin, Ireland.
Royal College of Surgeons in Ireland · IEKarolinska Institutet · SEUniversity College Cork · IECentral and North West London NHS Foundation Trust · GBHealth Service Executive · IENew York Psychoanalytic Society and Institute · USUniversity of Bern · CHUniversity of Molise · ITUniversity of Regensburg · DE

Funding

European Research Council 724809Science Foundation Ireland 16/RC/3948415Seventh Framework Programme HEALTH-F2-2009-223091Wellcome Trust 220438Z/20/Z
6 · The paper itself

Abstract

introductionPsychotic experiences (PEs) are associated with increased risk of later mental disorders and so could be valuable in prevention studies. However, to date few intervention studies have examined PEs. Given this lack of evidence, in the current study a secondary data analysis was conducted on a clustered-randomized control trial (RCT) of 3 school based interventions to reduce suicidal behaviour, to investigate if these may reduce rates of PEs, and prevent PE, at 3-month and 1-year follow-up.

methodsThe Irish site of the Saving and Empowering Young Lives in Europe study, trial registration (DRKS00000214), a cluster-RCT designed to examine the effect of school-based interventions on suicidal thoughts and behaviour. Seventeen schools (n = 1096) were randomly assigned to one of three intervention arms or a control arm. The interventions included a teacher training (gate-keeper) intervention, an interactive educational (universal-education) intervention, and a screening and integrated referral (selective-indicative) intervention. The primary outcome of this secondary data-analysis was reduction in point-prevalence of PEs at 12 months. A second analysis excluding those with PEs at baseline was conducted to examine prevention of PEs. Additional analysis was conducted of change in depression and anxiety scores (comparing those with/without PEs) in each arm of the intervention. Statistical analyses were conducted using mixed-effects modelling.

resultsAt 12-months, the screening and referral intervention was associated with a significant reduction in PEs (OR:0.12,95%CI[0.02-0.62]) compared to the control arm. The teacher training and education intervention did not show this effect. Prevention was also observed only in the screening and referral arm (OR:0.30,95%CI[0.09-0.97]). Participants with PEs showed higher levels of depression and anxiety symptoms, compared to those without, and different responses to the screening and referral intervention & universal-education intervention.

conclusionsThis study provides the first evidence for a school based intervention that reduce & prevent PEs in adolescence. This intervention is a combination of a school-based screening for psychopathology and subsequent referral intervention significantly reduced PEs in adolescents. Although further research is needed, our findings point to the effectiveness of school-based programmes for prevention of future mental health problems.

Indexed as

Mental DisordersSecondary Data AnalysisAdolescentAnxietyEuropeHumansSchoolsInterventionPreventionPsychosisPsychotic experiencesSchool based intervention

Identifiers

PMID36726107
PMCPMC9890687
OpenAlexW4318821372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.