Evidence map›Paper›PMID 36725787›Full record

ArticlePharmacoEconomics2023

Informal Care Costs According to Age and Proximity to Death to Support Cost-Effectiveness Analyses.

Saskia de Groot, Irene Santi, Pieter Bakx, Bram Wouterse, Pieter van Baal

Open access · hybridAbstract read
In one paragraph

Article in PharmacoEconomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Saskia de Groot *Institute for Medical Technology Assessment, Erasmus University Rotterdam, Rotterdam, The Netherlands. degroot@imta.eur.nl.
Irene Santi *Institute for Medical Technology Assessment, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Pieter BakxDepartment of Health Economics, Erasmus School of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Bram WouterseDepartment of Health Economics, Erasmus School of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Pieter van BaalDepartment of Health Economics, Erasmus School of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Erasmus University Rotterdam · NL

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related DementiasP01AG005842 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI KOSALI ILAYPERUMA SIMON · 1986 to 2026
$56.5M
WEALTH DISPARITIES AMONG MATURE AND OLDER ADULTSP01AG008291 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1989 to 2018
$19.4M
RAND CENTER FOR THE STUDY OF AGINGP30AG012815 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1999 to 2020
$13.7M
Enhancing the Comparability of SHARE with HRS and ELSAR01AG052527 · NIA · MAX PLANCK INST/SOCIAL LAW/SOCIAL POLICY · PI BOERSCH-SUPAN, AXEL H · 2016 to 2020
$2.1M
DEVELOPING AN ISRAELI VERSION OF THE HRS/SHARE PROJECTR21AG025169 · NIA · HEBREW UNIVERSITY OF JERUSALEM · PI LITWIN, HOWARD · 2004 to 2006
$297k
NIA NIH HHS P01 AG005842NIA NIH HHS P01 AG008291NIA NIH HHS P30 AG012815NIA NIH HHS R01 AG052527NIA NIH HHS R21 AG025169NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

backgroundCosts of informal care are ignored in many cost-effectiveness analyses (CEAs) conducted from a societal perspective; however, these costs are relevant for lifesaving interventions targeted at the older population. In this study, we estimated informal care costs by age and proximity to death across European regions and showed how these estimates can be included in CEAs.

methodsWe estimated informal care costs by age and proximity to death using generalised linear mixed-effects models. For this, we selected deceased singles from the Survey of Health, Ageing and Retirement, which we grouped by four European regions. We combined the estimates of informal care costs with life tables to illustrate the impact of including informal care costs on the incremental cost-effectiveness ratio (ICER) of a hypothetical intervention that prevents a death at different ages.

resultsInformal care use, and hence informal care costs, increase when approaching death and with increasing age. The impact of including informal care costs on the ICER varies between €200 and €17,700 per quality-adjusted life-year gained. The impact increases with age and is stronger for women and in southern European countries.

conclusionOur estimates of informal care costs facilitate including informal care costs in CEAs of life-extending healthcare interventions. Including these costs may influence decisions as it leads to reranking of life-extending interventions compared with interventions improving quality of life.

Indexed as

Patient CareQuality of LifeCost-Benefit AnalysisCost-Effectiveness AnalysisDelivery of Health CareFemaleHumansQuality-Adjusted Life Years

Identifiers

PMID36725787
PMCPMC10450016
OpenAlexW4318826232

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.