Evidence map›Paper›PMID 36725760›Full record

ArticleDysphagia2023

Peroral Endoscopic Myotomy for Achalasia in Older Adults: A Retrospective Analysis of 39 Cases with a Minimum Follow-Up of 5 Years.

Dongzi Peng, Yuyong Tan, Si Yang, Mei Zhou, Liang Lv, Chengbai Liang, Hongyi Zhu, Rong Li, Deliang Liu

Abstract read
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In one paragraph

Article in Dysphagia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dongzi PengDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.
Yuyong TanDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.
Si YangDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.
Mei ZhouDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.
Liang LvDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.
Chengbai LiangDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.
Hongyi ZhuDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.
Rong LiDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China. xylulr@csu.edu.cn.ORCID 0000-0003-2695-1640
Deliang LiuDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroral endoscopic myotomy (POEM) has demonstrated favorable short-term safety and efficacy in older adults, while a comprehensive understanding of the long-term outcomes were vague. We aimed to evaluate clinical outcomes in older adults' 5-year postop after undergoing POEM to treatment achalasia. Older adults from a single hospital who received POEM between January 2010 and January 2017 were analyzed. Older persons were reached to evaluate their symptoms at present and encouraged repeat examinations for objective follow-up. The clinical success, POEM-related indicators, POEM-related adverse events, and quality of life were assessed. Thirty-nine older adults with a mean age of 70.82 ± 4.72 who underwent POEM were studied at a mean 84.23 ± 25.06 month follow-up. The preoperative diagnosis was achalasia type I in 7 older adults, achalasia type II in 26 older adults, and achalasia type III in 2 older adults. Sixteen older adults had prior treatment and 21 older adults suffered from comorbidities. The median operative time was 50 (25-120) minutes, and perioperative adverse events were recorded in four older adults. The current Eckardt scores were significantly lower than that before POEM (2.08 ± 2.12 vs. 6.58 ± 1.78, P < 0.001). Besides, long-term clinical success was gained in 66.7% of older adults. Three older adults received postop treatment for symptom recurrence. Ultimately, 80.6% of old adults expressed satisfaction with POEM, while 27.8% of older adults suffered from symptomatic reflux. In conclusion, POEM can provide symptomatic improvement in a large proportion of older adults with achalasia at 5-year postop.

Indexed as

Esophageal AchalasiaMyotomyNatural Orifice Endoscopic SurgeryAgedAged, 80 and overEsophageal Sphincter, LowerEsophagoscopyFollow-Up StudiesHumansQuality of LifeRetrospective StudiesTreatment OutcomeEndoscopic surgeryEsophageal achalasiaLower esophageal sphincterOlder adultPeroral endoscopic myotomy

Identifiers

PMID36725760
OpenAlexW4318821667

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.