Evidence map›Paper›PMID 36725719›Full record

ArticleEuropean radiology2023

The added value of AI-based computer-aided diagnosis in classification of cancer at prostate MRI.

Guiqin Liu, Shihang Pan, Rui Zhao, Huang Zhou, Jie Chen, Xiang Zhou, Jianrong Xu, Yan Zhou, Wei Xue, Guangyu Wu

Abstract read
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In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Guiqin Liu *Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Shihang Pan *Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Rui ZhaoDepartment of Radiology, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Huang ZhouDepartment of Radiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Jie ChenHuangpu Branch, Shanghai Ninth People's Hospital, Shanghai, China.
Xiang ZhouDepartment of Radiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jianrong XuDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yan ZhouDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wei XueDepartment of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. WeiXue20200903@126.com.
Guangyu WuDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. danielrau@163.com.ORCID http://orcid.org/0000-0003-0546-9767
Shanghai Jiao Tong University · CNNanjing University of Chinese Medicine · CNShanghai East Hospital · CNShanghai Ninth People's Hospital · CNShanghai University of Traditional Chinese Medicine · CN

Funding

National Natural Science Foundation of China 81601453National Natural Science Foundation of China 81601487Shanghai Municipal Commission of Economy and Informatization 2019-RGZN-01094the Science and Technology Commission of Shanghai Municipality 18DZ1930104The shanghai Jiao Tong Unversity Medical Engineering Cross Fund YG2021QN27the Shanghai Pujiang Program 19PJ1431900
6 · The paper itself

Abstract

objectivesTo develop an artificial intelligence (AI) model for prostate segmentation and prostate cancer (PCa) detection, and explore the added value of AI-based computer-aided diagnosis (CAD) compared to conventional PI-RADS assessment.

methodsA retrospective study was performed on multi-centers and included patients who underwent prostate biopsies and multiparametric MRI. A convolutional-neural-network-based AI model was trained and validated; the reliability of different CAD methods (concurrent read and AI-first read) were tested in an internal/external cohort. The diagnostic performance, consistency and efficiency of radiologists and AI-based CAD were compared.

resultsThe training/validation/internal test sets included 650 (400/100/150) cases from one center; the external test included 100 cases (25/25/50) from three centers. For diagnosis accuracy, AI-based CAD methods showed no significant differences and were equivalent to the radiologists in the internal test (127/150 vs. 130/150 vs. 125/150 for reader 1; 127/150 vs.132/150 vs. 131/150 for reader 2; all p > 0.05), whereas in the external test, concurrent-read methods were superior/equal to AI-first read (87/100 vs. 71/100, p < 0.001, for reader 2; 79/100 vs. 69/100, p = 0.076, for reader 1) and better than/equal to radiologists (79/100 vs. 72/100, p = 0.039, for reader 1; 87/100 vs. 86/100, p = 1.000, for reader 2). Moreover, AI-first read/concurrent read improved consistency in both internal test (κ = 1.000, 0.830) and external test (κ = 0.958, 0.713) compared to radiologists (κ = 0.747, 0.600); AI-first read method (8.54 s/7.66 s) was faster than readers (92.72 s/89.54 s) and concurrent-read method (29.15 s/28.92 s), respectively.

conclusionAI-based CAD could improve the consistency and efficiency for accurate diagnosis; the concurrent-read method could enhance the diagnostic capabilities of an inexperienced radiologist in unfamiliar situations. KEY POINTS: • For prostate cancer segmentation, the performance of multi-small Vnet displays optimal compared to small Vnet and Vnet (DSC

Indexed as

Magnetic Resonance ImagingProstatic NeoplasmsArtificial IntelligenceComputersHumansMaleProstateReproducibility of ResultsRetrospective StudiesArtificial intelligenceMagnetic resonance imagingProstatic neoplasms

Identifiers

PMID36725719
OpenAlexW4318767440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.