Evidence map›Paper›PMID 36725341›Full record

ArticleeNeuro2023

Allopregnanolone Effects on Inhibition in Hippocampal Parvalbumin Interneurons.

Xinguo Lu, Peter Lambert, Ann Benz, Charles F Zorumski, Steven J Mennerick

Open access · goldFull text read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. A Role for δ Subunit-Containing GABAThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Article
  3. δ-Containing GABAJournal of neurophysiology · 2025
    Article
  4. Article
  5. Article
  6. GABAProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xinguo LuDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110 xinguolu@wustl.edu menneris@wustl.edu.
Peter LambertDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.
Ann BenzDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.
Charles F ZorumskiDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.ORCID https://orcid.org/0000-0002-9704-5154
Steven J MennerickDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110 xinguolu@wustl.edu menneris@wustl.edu.ORCID https://orcid.org/0000-0003-0868-0664
Washington University in St. Louis · US

Funding

Neuroactive steroids as novel psychiatric treatments: mechanistic studiesP50MH122379 · NIMH · WASHINGTON UNIVERSITY · PI MAGUIRE, JAMIE LYNN · 2021 to 2025
$12.2M
GABAA RECEPTOR POPULATIONS IN HIPPOCAMPUS AND THALAMUSR01MH123748 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2021 to 2025
$2.4M
Hippocampal circuit mechanisms of neurosteroidsF30MH126548 · NIMH · WASHINGTON UNIVERSITY · PI LAMBERT, PETER MICHAEL · 2021 to 2024
$171k
NIMH NIH HHS F30 MH126548NIMH NIH HHS P50 MH122379NIMH NIH HHS R01 MH123748
6 · The paper itself

Abstract

Allopregnanolone (AlloP) is a neurosteroid that potentiates ionotropic GABAergic (GABA

Indexed as

ParvalbuminsPregnanoloneAnimalsFemalegamma-Aminobutyric AcidHippocampusInterneuronsMaleMiceReceptors, GABA-Agamma-Aminobutyric AcidParvalbuminsPregnanoloneReceptors, GABA-Aantidepressantinhibitioninterneuronneurosteroid

Identifiers

PMID36725341
PMCPMC10012327
OpenAlexW4318768345

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read41
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.