Evidence map›Paper›PMID 36725050›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Aplastic Anemia with Epstein-Barr Virus Reactivation after Anti-thymocyte Globulin Therapy.

Yo Kawarada, Ryujiro Hara, Toshihiko Kitahara, Hiroki Numata, Shigeki Watanabe, Masatoshi Yamada, Kiyoshi Ando

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yo KawaradaDepartment of Hematology, Ebina General Hospital, Japan.
Ryujiro HaraDepartment of Hematology, Ebina General Hospital, Japan.
Toshihiko KitaharaDepartment of Hematology, Ebina General Hospital, Japan.
Hiroki NumataDepartment of Hematology, Ebina General Hospital, Japan.
Shigeki WatanabeDepartment of Hematology, Ebina General Hospital, Japan.
Masatoshi YamadaDepartment of Histopathology, Ebina General Hospital, Japan.
Kiyoshi AndoDivision of Hematology/Oncology, Department of Internal Medicine, Tokai University School of Medicine, Japan.
Ebina General Hospital · JPTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphoproliferative disorders and Epstein-Barr virus reactivation (EBV-LPDs) have various forms of onset, ranging from infectious mononucleosis-like syndrome (IM-like) to lymphoma, although whether or not IM-like progresses to lymphoma remains unclear. A 61-year-old man was diagnosed with aplastic anemia (AA). Polyclonal atypical B-lymphocytes were observed in the peripheral blood, and IM-like was diagnosed. Atypical lymphocytes disappeared, but a gastrointestinal examination revealed diffuse large B-cell lymphoma (DLBCL). Rituximab was initiated but later discontinued because of severe acute respiratory syndrome coronavirus 2 infection. Pancytopenia due to AA exacerbation recurred. The patient ultimately died of multiple organ failure due to bacterial infection.

Indexed as

Anemia, AplasticCOVID-19Epstein-Barr Virus InfectionsLymphoma, Large B-Cell, DiffuseAntilymphocyte SerumHerpesvirus 4, HumanHumansMaleMiddle AgedNeoplasm Recurrence, LocalAntilymphocyte Serumanti-thymocyte globulinaplastic anemiaEpstein-Barr virusinfectious mononucleosis-like syndromelymphoproliferative disorders

Identifiers

PMID36725050
PMCPMC10518559
OpenAlexW4318689659

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.