Evidence map›Paper›PMID 36725044›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Anti-neutrophil Cytoplasmic Antibody-negative Eosinophilic Granulomatosis with Polyangiitis Complicated with Peripheral Neuropathy that Underwent Remission Induction with Mepolizumab Monotherapy.

Masahiro Nishihara, Midori Suzuki, Shinya Asatani, Yosuke Nagasawa, Masako Tsukamoto, Kumiko Akiya, Hitomi Kobayashi, Noboru Kitamura, Hideki Nakamura

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Masahiro NishiharaDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Midori SuzukiDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Shinya AsataniDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Yosuke NagasawaDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Masako TsukamotoDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Kumiko AkiyaDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Hitomi KobayashiDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Noboru KitamuraDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Hideki NakamuraDivision of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, Japan.
Nihon University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 72-year-old woman was admitted to our hospital with numbness in her lower extremities and hypereosinophilia. She was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA). On admission, she was suspected of being complicated with pneumonia and sepsis; therefore, treatment with mepolizumab monotherapy was begun, resulting in partial improvement. After the possibility of a complicating infection was ruled out, corticosteroids were initiated, followed by intravenous gamma globulin therapy. Although the induction of remission of EGPA with mepolizumab monotherapy is not usually recommended, induction with mepolizumab monotherapy may be an option in terms of safety and clinical efficacy in some cases.

Indexed as

Churg-Strauss SyndromeGranulomatosis with PolyangiitisPeripheral Nervous System DiseasesAgedAntibodies, Antineutrophil CytoplasmicAntibodies, Monoclonal, HumanizedFemaleHumansRemission InductionAntibodies, Antineutrophil CytoplasmicAntibodies, Monoclonal, HumanizedmepolizumabEGPAmepolizumabmonotherapyperipheral neuropathy

Identifiers

PMID36725044
PMCPMC10602846
OpenAlexW4318689587

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.