Evidence map›Paper›PMID 36725043›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Coexistence of Pheochromocytoma and Primary Aldosteronism due to Multiple Aldosterone-producing Micronodules in the Ipsilateral Adrenal Gland.

Satoshi Ugi, Maya Yonishi, Daisuke Sato, Nobuhiko Nakaizumi, Osamu Horikawa, Yukihiro Fujita, Kentaro Inoue, Akinori Wada, Susumu Kageyama, Akihiro Kawauchi and 5 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Epigenomic Alterations of the HumanInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Satoshi UgiDepartment of Medicine, Shiga University of Medical Science, Japan.
Maya YonishiDepartment of Medicine, Shiga University of Medical Science, Japan.
Daisuke SatoDepartment of Medicine, Shiga University of Medical Science, Japan.
Nobuhiko NakaizumiDepartment of Medicine, Shiga University of Medical Science, Japan.
Osamu HorikawaDepartment of Medicine, Shiga University of Medical Science, Japan.
Yukihiro FujitaDepartment of Medicine, Shiga University of Medical Science, Japan.
Kentaro InoueDepartment of Urology, Shiga University of Medical Science, Japan.
Akinori WadaDepartment of Urology, Shiga University of Medical Science, Japan.
Susumu KageyamaDepartment of Urology, Shiga University of Medical Science, Japan.
Akihiro KawauchiDepartment of Urology, Shiga University of Medical Science, Japan.
Michiko HinoDepartment of Pathology, Shiga University of Medical Science, Japan.
Mai NoujimaDepartment of Pathology, Shiga University of Medical Science, Japan.
Yuto YamazakiDepartment of Pathology, Tohoku University Graduate School of Medicine, Japan.
Hironobu SasanoDepartment of Pathology, Tohoku University Graduate School of Medicine, Japan.
Hiroshi MaegawaDepartment of Medicine, Shiga University of Medical Science, Japan.
Shiga University of Medical Science · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 46-year-old woman was referred for hypertension and a right adrenal tumor. Primary aldosteronism (PA) was suspected because of the high plasma aldosterone concentration-to-plasma renin activity ratio. However, a subsequent evaluation revealed coexistent PA and pheochromocytoma. We performed laparoscopic right adrenalectomy. Histology of the resected adrenal gland confirmed pheochromocytoma and multiple aldosterone-producing adrenocortical micronodules. Following adrenalectomy, the urinary catecholamine levels normalized, and hyperaldosteronism improved but persisted. Hypertension also improved but persisted and was normalized with spironolactone. The clinical course indicated that the PA lesions were likely bilateral. This was a histologically proven case of coexistent pheochromocytoma and PA due to multiple aldosterone-producing micronodules.

Indexed as

Adrenal Gland NeoplasmsHyperaldosteronismHypertensionPheochromocytomaAdrenalectomyAdrenal GlandsAldosteroneFemaleHumansMiddle AgedAldosteronecoexistenceCYP11B2multiple aldosterone-producing micronodulespheochromocytomaprimary aldosteronism

Identifiers

PMID36725043
PMCPMC10569916
OpenAlexW4318689360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.