Evidence map›Paper›PMID 36725035›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Allergy to Omalizumab: Lessons from a Reaction to the Coronavirus 2019 Vaccine.

Takeshi Matsumoto, Yumiko Sakurai, Takahiro Fujiki, Yusuke Kusakabe, Emi Nakayama, Ayaka Tanaka, Naoki Yamamoto, Kensaku Aihara, Shinpachi Yamaoka, Michiaki Mishima

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Takeshi MatsumotoDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Yumiko SakuraiDepartment of Dermatology, Saiseikai-Noe Hospital, Japan.
Takahiro FujikiDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Yusuke KusakabeDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Emi NakayamaDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Ayaka TanakaDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Naoki YamamotoDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Kensaku AiharaDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Shinpachi YamaokaDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Michiaki MishimaDepartment of Respiratory Medicine, Saiseikai-Noe Hospital, Japan.
Saiseikai Ibaraki Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omalizumab can cause hypersensitivity reactions. We herein report the first case of an 18-year-old woman with refractory cough-predominant asthma that correlated with allergic reactions caused by omalizumab and the coronavirus disease 2019 (COVID-19) vaccine. The patient developed angioedema after taking omalizumab. She had previously experienced intense coughing immediately after receiving a COVID-19 vaccine. A skin prick test was positive for polysorbate 20, which was probably the cause of the allergic reactions to omalizumab and the COVID-19 vaccine. Clinicians should check for an allergic reaction, irrespective of its intensity, triggered by polysorbate and be careful when prescribing biologics to patients in order to avoid allergic reactions.

Indexed as

AngioedemaAnti-Allergic AgentsCOVID-19COVID-19 VaccinesOmalizumabAdolescentAntibodies, Monoclonal, HumanizedCoronavirusFemaleHumansPolysorbatesAnti-Allergic AgentsAntibodies, Monoclonal, HumanizedCOVID-19 VaccinesOmalizumabPolysorbatesallergyangioedemacoronavirus disease 2019omalizumabpolysorbate

Identifiers

PMID36725035
PMCPMC10183271
OpenAlexW4318689308

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.