ArticleProceedings of the National Academy of Sciences of the United States of America2023
Distinct early and late neural mechanisms regulate feature-specific sensory adaptation in the human visual system.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 44 citations in OpenAlex.
- Late Cross-Modal Biases in Neural Spatial Representations Revealed by EEG Decoding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Deviance detection via competitive inhibition between local neocortical ensembles.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Faster but less precise: expectation enhances response speed while reducing sensory fidelity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Alpha frequency shapes perceptual sensitivity by modulating optimal phase likelihood.Nature communications · 2026Article
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- Investigating orientation adaptation following naturalistic film viewing.Scientific reports · 2025Article
- Deviance detection via competitive inhibition between local neocortical ensembles.bioRxiv : the preprint server for biology · 2025Article
- Reply to: "Model mimicry limits conclusions about neural tuning and can mistakenly imply unlikely priors".Nature communications · 2025Article
- Model mimicry limits conclusions about neural tuning and can mistakenly imply unlikely priors.Nature communications · 2025Article
- Stimulus Repetition Induces a Two-Stage Learning Process in the Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Limited Evidence for Probabilistic Cueing Effects on Grating-Evoked Event-Related Potentials and Orientation Decoding Performance.Psychophysiology · 2025Article
- Violated predictions enhance the representational fidelity of visual features in perception.Journal of vision · 2025Article
- Reactivation of previous decisions repulsively biases sensory encoding but attractively biases decision-making.PLoS biology · 2025Article
- Multimodal evidence challenges the effectiveness of probabilistic cueing for establishing sensory expectations.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Electroencephalography-based neural indicators of texture preference for cosmetic formulations.Frontiers in neuroscience · 2025Article
- Task-related modulation of event-related potentials does not reflect changes to sensory representations.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Neural tuning instantiates prior expectations in the human visual system.Nature communications · 2023Article
- Distinct early and late neural mechanisms regulate feature-specific sensory adaptation in the human visual system.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A canonical feature of sensory systems is that they adapt to prolonged or repeated inputs, suggesting the brain encodes the temporal context in which stimuli are embedded. Sensory adaptation has been observed in the central nervous systems of many animal species, using techniques sensitive to a broad range of spatiotemporal scales of neural activity. Two competing models have been proposed to account for the phenomenon. One assumes that adaptation reflects reduced neuronal sensitivity to sensory inputs over time (the "fatigue" account); the other posits that adaptation arises due to increased neuronal selectivity (the "sharpening" account). To adjudicate between these accounts, we exploited the well-known "tilt aftereffect", which reflects adaptation to orientation information in visual stimuli. We recorded whole-brain activity with millisecond precision from human observers as they viewed oriented gratings before and after adaptation, and used inverted encoding modeling to characterize feature-specific neural responses. We found that both fatigue and sharpening mechanisms contribute to the tilt aftereffect, but that they operate at different points in the sensory processing cascade to produce qualitatively distinct outcomes. Specifically, fatigue operates during the initial stages of processing, consistent with tonic inhibition of feedforward responses, whereas sharpening occurs ~200 ms later, consistent with feedback or local recurrent activity. Our findings reconcile two major accounts of sensory adaptation, and reveal how this canonical process optimizes the detection of change in sensory inputs through efficient neural coding.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.