Evidence map›Paper›PMID 36724252›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Endogenous circadian reporters reveal functional differences of

Jiyoung Park, Kwangjun Lee, Hyeongseok Kim, Heungsop Shin, Choogon Lee

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Oligomerization of PER2 as a dynamic mode of regulation of the mammalian circadian clock.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Deletion of Clock GeneClocks & sleep · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Circadian Control of Protein Synthesis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  11. PERspectives on circadian cell biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  12. Review
  13. Article
  14. Natural Compounds that Modulate Circadian Rhythms.Current topics in medicinal chemistry · 2025
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiyoung ParkDepartment of Biomedical Sciences, Program in Neuroscience, College of Medicine, Florida State University, Tallahassee, FL 32306.
Kwangjun LeeDepartment of Biomedical Sciences, Program in Neuroscience, College of Medicine, Florida State University, Tallahassee, FL 32306.
Hyeongseok KimDepartment of Chemical Engineering and Biotechnology, Tech University of Korea 15073 237, Gyeonggi-do, Republic of Korea.
Heungsop ShinDepartment of Chemical Engineering and Biotechnology, Tech University of Korea 15073 237, Gyeonggi-do, Republic of Korea.ORCID 0000-0001-5913-7608
Choogon LeeDepartment of Biomedical Sciences, Program in Neuroscience, College of Medicine, Florida State University, Tallahassee, FL 32306.ORCID 0000-0002-6052-4944

Funding

Molecular mechanisms underlying human circadian sleep disordersR01GM131283 · NIGMS · FLORIDA STATE UNIVERSITY · PI LEE, CHOOGON · 2019 to 2022
$1.2M
NIGMS NIH HHS R01 GM131283
6 · The paper itself

Abstract

Adverse consequences from having a faulty circadian clock include compromised sleep quality and poor performance in the short-term, and metabolic diseases and cancer in the long-term. However, our understanding of circadian disorders is limited by the incompleteness of our molecular models and our dearth of defined mutant models. Because it would be prohibitively expensive to develop live animal models to study the full range of complicated clock mechanisms, we developed

Indexed as

Circadian ClocksCircadian RhythmPeriod Circadian ProteinsAnimalsMicePhosphorylationPer1 protein, mousePer2 protein, mousePeriod Circadian Proteinsbioluminescencecircadiancrisprperiodreporter

Identifiers

PMID36724252
PMCPMC9962996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.