Evidence map›Paper›PMID 36724083›Full record

ArticleInorganic chemistry2023

Sc-HOPO: A Potential Construct for Use in Radioscandium-Based Radiopharmaceuticals.

Michael D Phipps, Shelbie Cingoranelli, N V S Dinesh K Bhupathiraju, Ali Younes, Minhua Cao, Vanessa A Sanders, Michelle C Neary, Matthew H Devany, Cathy S Cutler, Gustavo E Lopez and 7 more

Abstract read
In one paragraph

Article in Inorganic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Towards the Stable Chelation of Radioantimony(V) for Targeted Auger Theranostics.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. [ACS omega · 2025
    Article
  6. Article
  7. Improving the In Vivo Stability of [Journal of medicinal chemistry · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Michael D PhippsPh.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, New York10016, United States.
Shelbie CingoranelliDepartment of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama35294, United States.
N V S Dinesh K BhupathirajuDepartment of Chemistry, City University of New York Hunter College, 695 Park Avenue, New York, New York10065, United States.ORCID 0000-0002-5885-3722
Ali YounesDepartment of Chemistry, City University of New York Hunter College, 695 Park Avenue, New York, New York10065, United States.ORCID 0000-0001-7351-2726
Minhua CaoDepartment of Chemistry, City University of New York Hunter College, 695 Park Avenue, New York, New York10065, United States.
Vanessa A SandersMedical Isotope Research and Production Laboratory, Collider-Accelerator Division, Brookhaven National Laboratory (BNL), Upton, New York11973, United States.
Michelle C NearyDepartment of Chemistry, City University of New York Hunter College, 695 Park Avenue, New York, New York10065, United States.ORCID 0000-0003-2805-3668
Matthew H DevanyDepartment of Chemistry, City University of New York Hunter College, 695 Park Avenue, New York, New York10065, United States.
Cathy S CutlerMedical Isotope Research and Production Laboratory, Collider-Accelerator Division, Brookhaven National Laboratory (BNL), Upton, New York11973, United States.
Gustavo E LopezPh.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, New York10016, United States.ORCID 0000-0003-1660-547X
Shefali SainiDepartment of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama35294, United States.
Candace C ParkerDepartment of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama35294, United States.ORCID 0000-0001-6744-7438
Solana R FernandezDepartment of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama35294, United States.
Jason S LewisProgram in Molecular Pharmacology and Chemistry, Memorial Sloan Kettering Cancer Center, New York, New York10065, United States.ORCID 0000-0001-7065-4534
Suzanne E LapiDepartment of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama35294, United States.
Lynn C FrancesconiPh.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, New York10016, United States.ORCID 0000-0001-6314-2899
Melissa A DeriPh.D. Program in Chemistry, The Graduate Center of the City University of New York, New York, New York10016, United States.ORCID 0000-0003-4186-5572

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Leveraging Pb-203/212 for the Theranostic Imaging and Therapy of Prostate CancerR35CA232130 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI LEWIS, JASON S. · 2019 to 2025
$8.2M
Chelator development for improved scandium theranostic agentsSC2GM130464 · NIGMS · HERBERT H. LEHMAN COLLEGE · PI DERI, MELISSA A · 2019 to 2021
$495k
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA013148NCI NIH HHS R35 CA232130NIGMS NIH HHS SC2 GM130464
6 · The paper itself

Abstract

Three isotopes of scandium─

Indexed as

PyridonesRadiopharmaceuticalsAnimalsChelating AgentsLigandsMicePositron-Emission TomographyChelating AgentsLigandsPyridonesRadiopharmaceuticals

Identifiers

PMID36724083
PMCPMC10390652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.