Evidence map›Paper›PMID 36723833›Full record

ArticleAnnals of biomedical engineering2023

A Comparison of Vessel Patch Materials in Tetralogy of Fallot Patients Using Virtual Surgery Techniques.

Alessia Di Nardo, Leslie Louvelle, David A Romero, Matthew Doyle, Thomas L Forbes, Cristina H Amon

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Annals of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alessia Di NardoDepartment of Mechanical Engineering, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L7, Canada. dinardoa@mcmaster.ca.ORCID http://orcid.org/0000-0001-5810-648X
Leslie LouvelleInstitute of Biomedical Engineering, University of Toronto, Toronto, Canada.
David A RomeroDepartment of Mechanical and Industrial Engineering, University of Toronto, Toronto, Canada.
Matthew DoyleDepartment of Mechanical and Industrial Engineering, University of Toronto, Toronto, Canada.
Thomas L ForbesDivision of Vascular Surgery, Department of Surgery, Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Canada.
Cristina H AmonInstitute of Biomedical Engineering, University of Toronto, Toronto, Canada.
University of Toronto · CAMcMaster University · CAUniversity Health Network · CA

Funding

Natural Sciences and Engineering Research Council 540369
6 · The paper itself

Abstract

Tetralogy of Fallot (ToF) is characterized by stenosis causing partial obstruction of the right ventricular outflow tract, typically alleviated through the surgical application of a vessel patch made from a biocompatible material. In this study, we use computational simulations to compare the mechanical performance of four patch materials for various stenosis locations. Nine idealized pre-operative ToF geometries were created by imposing symmetrical stenoses on each of three anatomical sub-regions of the pulmonary arteries of three patients with previously repaired ToF. A virtual surgery methodology was implemented to replicate the steps of vessel de-pressurization, surgical patching, and subsequent vessel expansion after reperfusion. Significant differences in patch average stress (p < 0.001) were found between patch materials. Biological patch materials (porcine xenopericardium, human pericardium) exhibited higher patch stresses in comparison to synthetic patch materials (Dacron and PTFE). Observed differences were consistent across the various stenosis locations and were insensitive to patient anatomy.

Indexed as

Tetralogy of FallotAnimalsConstriction, PathologicHeart VentriclesHumansPericardiumPulmonary ArterySwineCongenital heart defectRight ventricular outflow tractVirtual surgery

Identifiers

PMID36723833
OpenAlexW4318753620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.