Evidence map›Paper›PMID 36723823›Full record

ReviewJournal of neurovirology2023

Undetectable JC virus CSF PCR in patients with JC virus-induced progressive multifocal leukoencephalopathy.

Chia-Yu Chiu, Eva Amenta, Violeta Chavez, Yuriko Fukuta, Rodrigo Hasbun

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neurovirology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chia-Yu ChiuDivision of Infectious Diseases, Department of Internal Medicine, The University of Texas Health Science Center at Houston, 6431 Fannin St, STE MSB 2112, Houston, TX, USA. chia-yu.chiu@uth.tmc.edu.ORCID 0000-0002-5241-3435
Eva AmentaSection of Infectious Diseases, Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA.
Violeta ChavezDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Yuriko FukutaSection of Infectious Diseases, Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA.
Rodrigo HasbunDivision of Infectious Diseases, Department of Internal Medicine, The University of Texas Health Science Center at Houston, 6431 Fannin St, STE MSB 2112, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of progressive multifocal leukoencephalopathy (PML) is based on a combination of clinical, radiographic, and laboratory findings. However, negative JC polyomavirus (JCPyV) PCR in CSF does not always rule out JCPyV-related PML. In this narrative review, we sought to examine the characteristic of biopsy-proven PML in patients with undetectable JCPyV CSF PCR and provide alternative approaches in this scenario.

Indexed as

JC VirusLeukoencephalopathy, Progressive MultifocalHumansPolymerase Chain ReactionBK virusBrainstemCerebellumJC virusPosterior fossaProgressive multifocal leukoencephalopathy

Identifiers

PMID36723823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.