Evidence map›Paper›PMID 36723703›Full record

ArticleApplied microbiology and biotechnology2023

Use of adjuvant ISA VG 71 to produce neutralizing egg yolk antibodies against bothropic venom.

Carlos Leónidas Leiva, Adriana Cangelosi, Virginia Mariconda, Ana Celi, Patricia Joaquim, Patricia Geoghegan, Mariano Fernández-Miyakawa, Pablo Chacana

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. IgY Antibodies from Birds: A Review on Affinity and Avidity.Animals : an open access journal from MDPI · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Carlos Leónidas LeivaInstituto de Patobiología, Instituto Nacional de Tecnología Agropecuaria, Nicolas Repetto y Los Reseros S/N, Hurlingham, Buenos Aires, Argentina. leiva.carlos@inta.gob.ar.ORCID http://orcid.org/0000-0001-9796-5092
Adriana CangelosiCentro Nacional de Control de Calidad de Biológicos, ANLIS "Dr. Carlos G. Malbrán", Av. Vélez Sarsfield, 563, CABA, Argentina.
Virginia MaricondaCentro Nacional de Control de Calidad de Biológicos, ANLIS "Dr. Carlos G. Malbrán", Av. Vélez Sarsfield, 563, CABA, Argentina.
Ana CeliInstituto de Patobiología, Instituto Nacional de Tecnología Agropecuaria, Nicolas Repetto y Los Reseros S/N, Hurlingham, Buenos Aires, Argentina.
Patricia JoaquimInstituto de Patobiología, Instituto Nacional de Tecnología Agropecuaria, Nicolas Repetto y Los Reseros S/N, Hurlingham, Buenos Aires, Argentina.
Patricia GeogheganCentro Nacional de Control de Calidad de Biológicos, ANLIS "Dr. Carlos G. Malbrán", Av. Vélez Sarsfield, 563, CABA, Argentina.ORCID https://orcid.org/0000-0002-3500-5181
Mariano Fernández-MiyakawaInstituto de Patobiología, Instituto Nacional de Tecnología Agropecuaria, Nicolas Repetto y Los Reseros S/N, Hurlingham, Buenos Aires, Argentina.
Pablo ChacanaInstituto de Patobiología, Instituto Nacional de Tecnología Agropecuaria, Nicolas Repetto y Los Reseros S/N, Hurlingham, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-2824-8385
Consejo Nacional de Investigaciones Científicas y Técnicas · ARAdministración Nacional de Laboratorios e Institutos de Salud · ARNational Institute of Industrial Technology · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of egg yolk antibodies-IgY technology-represents an alternative to the production of mammalian immunoglobulins and has several advantages regarding animal welfare and lower costs of production. The use of adjuvants to achieve the hyperimmunization of laying hens plays a key role in the success of the production of high levels of the antibodies. In the present work, two different adjuvant systems (Freund's adjuvants and Montanide

Indexed as

Antibodies, NeutralizingVenomsAdjuvants, ImmunologicAdjuvants, PharmaceuticAnimalsChickensEgg YolkFemaleFreund's AdjuvantImmunoglobulinsMammalsMiceMineral OilAdjuvants, ImmunologicAdjuvants, PharmaceuticAntibodies, NeutralizingFreund's AdjuvantImmunoglobulinsMineral OilMonatide (IMS 3015)VenomsAdjuvantEgg yolkIgY antibodyMass spectrometryMontanide

Identifiers

PMID36723703
OpenAlexW4318755397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.