Evidence map›Paper›PMID 36722732›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Advances of Antimicrobial Peptide-Based Biomaterials for the Treatment of Bacterial Infections.

Guoyu Li, Zhenheng Lai, Anshan Shan

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
34.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 185 citations in OpenAlex.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Guoyu LiThe Institute of Animal Nutrition, Northeast Agricultural University, Harbin, 150030, P. R. China.
Zhenheng LaiThe Institute of Animal Nutrition, Northeast Agricultural University, Harbin, 150030, P. R. China.ORCID 0000-0002-6450-4051
Anshan ShanThe Institute of Animal Nutrition, Northeast Agricultural University, Harbin, 150030, P. R. China.ORCID 0000-0003-2830-7509
Northeast Agricultural University · CN

Funding

Heilongjiang Touyan Innovation Team Program 54600112National Natural Science Foundation of China 31872368National Natural Science Foundation of China 32030101National Natural Science Foundation of China 32272914
6 · The paper itself

Abstract

Owing to the increase in multidrug-resistant bacterial isolates in hospitals globally and the lack of truly effective antimicrobial agents, antibiotic resistant bacterial infections have increased substantially. There is thus an urgent need to develop new antimicrobial drugs and their related formulations. In recent years, natural antimicrobial peptides (AMPs), AMP optimization, self-assembled AMPs, AMP hydrogels, and biomaterial-assisted delivery of AMPs have shown great potential in the treatment of bacterial infections. In this review, it is focused on the development prospects and shortcomings of various AMP-based biomaterials for treating animal model infections, such as abdominal, skin, and eye infections. It is hoped that this review will inspire further innovations in the design of AMP-based biomaterials for the treatment of bacterial infections and accelerate their commercialization.

Indexed as

Anti-Infective AgentsBacterial InfectionsAnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesBiocompatible MaterialsAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesBiocompatible Materialsantimicrobial peptidesbacterial infectionbiomaterial deliverydesign strategymouse modelstreatment potential

Identifiers

PMID36722732
PMCPMC10104676
OpenAlexW4318754488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.