Evidence map›Paper›PMID 36722618›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2023

Scaffold Remodelling of Diazaspirotricycles Enables Synthesis of Diverse sp

Ephraim A Okolo, Axel Pahl, Sonja Sievers, Christopher M Pask, Adam Nelson, Stephen P Marsden

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Scaffold Remodelling of Diazaspirotricycles Enables Synthesis of Diverse spChemistry (Weinheim an der Bergstrasse, Germany) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ephraim A OkoloSchool of Chemistry, University of Leeds, Leeds, LS2 9JT, UK.
Axel PahlMax-Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, Dortmund, 44227, Germany.ORCID http://orcid.org/0000-0003-2068-7543
Sonja SieversMax-Planck Institute of Molecular Physiology, Department of Chemical Biology, Otto-Hahn-Strasse 11, Dortmund, 44227, Germany.
Christopher M PaskSchool of Chemistry, University of Leeds, Leeds, LS2 9JT, UK.
Adam NelsonSchool of Chemistry, University of Leeds, Leeds, LS2 9JT, UK.ORCID http://orcid.org/0000-0003-3886-363X
Stephen P MarsdenSchool of Chemistry, University of Leeds, Leeds, LS2 9JT, UK.ORCID http://orcid.org/0000-0002-2723-8954

Funding

Engineering and Physical Sciences Research Council EP/N025652/1Engineering and Physical Sciences Research Council EP/W002914/1Tertiary Education Trust Fund
6 · The paper itself

Abstract

A 'top down' scaffold remodelling approach to library synthesis was applied to spirotricyclic ureas prepared by a complexity-generating oxidative dearomatisation. Eighteen structurally-distinct, sp

Indexed as

Small Molecule LibrariesGene LibrarySmall Molecule Librariesdearomatisationlibrary synthesismolecular diversityphenotypic screening

Identifiers

PMID36722618
PMCPMC10946999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.