Evidence map›Paper›PMID 36722049›Full record

ArticleThe journal of physical chemistry. B2023

Effects of Water Deuteration on Thermodynamic and Structural Properties of Proteins and Biomembranes.

Carmelo Tempra, Victor Cruces Chamorro, Pavel Jungwirth

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Article in The journal of physical chemistry. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Water at Lipid Interfaces: Domains and Defects.Sub-cellular biochemistry · 2026
    Review
  4. Article
  5. Constitutive activity of the sweet taste receptor: Heavy water sweetness and beyond.Protein science : a publication of the Protein Society · 2025
    Review
  6. Article
  7. Article
  8. Hydration (HJournal of the American Chemical Society · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Elucidating the role of water in collagen self-assembly by isotopically modulating collagen hydration.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. DThe journal of physical chemistry. B · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carmelo TempraInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 160 00 Prague 6, Czech Republic.ORCID 0000-0002-2890-6993
Victor Cruces ChamorroInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 160 00 Prague 6, Czech Republic.
Pavel JungwirthInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 160 00 Prague 6, Czech Republic.ORCID 0000-0002-6892-3288

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light and heavy water are often used interchangeably in spectroscopic experiments with the tacit assumption that the structure of the investigated biomolecule does not depend too much on employing one or the other solvent. While this may often be a good approximation, we demonstrate here using molecular dynamics simulations incorporating nuclear quantum effects via modification of the interaction potential that there are small but significant differences. Namely, as quantified and discussed in the present study, both proteins and biomembranes tend to be slightly more compact and rigid in D

Indexed as

ProteinsWaterDeuterium OxideSolventsThermodynamicsDeuterium OxideProteinsSolventsWater

Identifiers

PMID36722049
PMCPMC10017026

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read14
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.