Evidence map›Paper›PMID 36722028›Full record

ArticleDevelopmental medicine and child neurology2023

Executive function and behaviour problems in school-age children born at risk of neonatal hypoglycaemia.

Darren W T Dai, Nike Franke, Christopher J D McKinlay, Trecia A Wouldes, Gavin T L Brown, Rajesh Shah, Samson Nivins, Jane E Harding, Children With Hypoglycaemia and Their Later Development (CHYLD) Study Group

Open access · hybridAbstract read
In one paragraph

Article in Developmental medicine and child neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Stability of executive function in children born at risk of neonatal hypoglycemia.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Darren W T DaiLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-2422-7448
Nike FrankeLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID 0000-0001-9240-3111
Christopher J D McKinlayLiggins Institute, University of Auckland, Auckland, New Zealand.
Trecia A WouldesDepartment of Psychological Medicine, University of Auckland, Auckland, New Zealand.
Gavin T L BrownFaculty of Education and Social Work, University of Auckland, Auckland, New Zealand.
Rajesh ShahLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-3175-7845
Samson NivinsLiggins Institute, University of Auckland, Auckland, New Zealand.
Jane E HardingLiggins Institute, University of Auckland, Auckland, New Zealand.
Children With Hypoglycaemia and Their Later Development (CHYLD) Study Group
University of Auckland · NZ

Funding

"Two year outcomes after dextrose gel prophylaxis for neonatal hypoglycaemia"R01HD091075 · NICHD · UNIVERSITY OF AUCKLAND · PI HARDING, JANE · 2018 to 2022
$2.0M
Children with Hypoglycemia and their Later Development (the CHYLD Study)R01HD069622 · NICHD · UNIVERSITY OF AUCKLAND · PI HARDING, JANE · 2011 to 2015
$1.7M
NICHD NIH HHS R01 HD069622NICHD NIH HHS R01 HD091075
6 · The paper itself

Abstract

aimTo examine the relationship between neonatal hypoglycaemia and specific areas of executive function and behaviour in mid-childhood.

methodParticipants in a prospective cohort study of infants born late preterm or at term at risk of neonatal hypoglycaemia were assessed at 9 to 10 years. We assessed executive function using performance-based (Cambridge Neuropsychological Tests Automated Battery) and questionnaire-based (Behavior Rating Inventory of Executive Function) measures and behaviour problems with the Strengths and Difficulties Questionnaire. Data are reported as adjusted odds ratio (aOR) with 95% confidence intervals, and standardized regression coefficients.

resultsWe assessed 480 (230 females, 250 males; mean age 9 years 5 months [SD 4 months, range 8 years 8 months-11 years 0 months]) of 587 eligible children (82%). There were no differences in performance-based executive function between children who did and did not experience neonatal hypoglycaemia (blood glucose <2.6 mmoL/L). However, children who experienced hypoglycaemia, especially if severe or recurrent, were at greater risk of parent-reported metacognition difficulties (aOR 2.37-3.71), parent-reported peer (aOR 1.62-1.89) and teacher-reported conduct (aOR 2.14 for severe hypoglycaemia) problems. Both performance- and questionnaire-based executive functions were associated with behaviour problems.

interpretationNeonatal hypoglycaemia may be associated with difficulties in specific aspects of parent-reported executive functions and behaviour problems in mid-childhood.

Indexed as

HypoglycemiaProblem BehaviorChildExecutive FunctionFemaleHumansInfantInfant, NewbornMaleNeuropsychological TestsProspective Studies

Identifiers

PMID36722028
PMCPMC10387501
OpenAlexW4318755268

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.