ArticleTobacco induced diseases2023
Smoking, e-cigarettes and the effect on respiratory symptoms among a population sample of youth: Retrospective cohort study.
Article in Tobacco induced diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- The Effect of Cigarettes and E-Cigarettes on Epithelial-Derived Extracellular Vesicles: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- Pooled it
- From Aerosol to Epithelium: An Integrated Clinical, Pathologic, and Mechanistic Review of Nicotine and Cannabis Vaporizer Use and Pulmonary Disease.Current allergy and asthma reports · 2026Review
- Article
- E-Cigarette Use Trajectories and Respiratory Symptoms in Adolescents and Young Adults: Sustained Use Linked to Greater Symptom Frequency.Journal of studies on alcohol and drugs · 2026Article
- Article
- Assessing the Italian version of the respiratory symptom experience scale (IT-RSES) in smokers and former smokers: a validation study.BMC public health · 2025Article
- Prevalence and correlates of negative side effects from vaping nicotine: Findings from the 2020 ITC four country smoking and vaping survey.Drug and alcohol dependence · 2025Article
- The association between e-cigarette use among Chinese college students and lung function and physical activity: A cross-sectional study.Tobacco induced diseases · 2025Article
- The association between electronic cigarette use and respiratory symptoms among university students: A cross-sectional study in Saudi Arabia.Tobacco induced diseases · 2025Article
- Vaping Possible Negative Effects on Lungs: State-of-the-Art From Lung Capacity Alteration to Cancer.Cureus · 2024Review
- Article
- Airway Proteotypes of E-Cigarette Users Overlap with Those Found in Asthmatics.American journal of respiratory cell and molecular biology · 2024Article
- Fruit flavors in electronic cigarettes (ECIGs) are associated with nocturnal dry cough: A population longitudinal analysis.PloS one · 2024Article
- Electronic cigarette use in relation to changes in smoking status and respiratory symptoms.Tobacco induced diseases · 2024Article
- E-cigarette use and respiratory symptoms in adults: A systematic review and meta-analysis.Tobacco induced diseases · 2023Review
- [Prevalence of electronic cigarette use and refill compositions among young people and adults in Cantabria].Open respiratory archivesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionE-cigarettes have been steadily increasing in popularity, both as cessation methods for smoking and for recreational and social reasons. This increase in vaping may pose cardiovascular and respiratory risks. We aimed to assess respiratory symptoms in youth users of e-cigarettes and cigarettes.
methodsA retrospective survey design was utilized to assess Canadian youth aged 16-25 years. Participants were recruited from the Ontario Tobacco Research Unit Youth and Young Adult Research Registration Panel November 2020 to March 2021. A total of 3082 subjects completed the baseline survey. Of these, 2660 individuals who did not have asthma were included in the analysis. The exposure of interest was pack-equivalent years, a novel measure of vaping exposure equivalent conceptually to cigarette pack years incorporating number of puffs per day, number of days vaped per month, and number of years vaped. Respiratory symptoms were measured using the five-item Canadian Lung Health Test. Poisson regression analyses were performed while adjusting for demographic confounders, stratified by smoking status. A non-stratified model tested the interaction of status and vaping dose and the effect of vaping device used was assessed among ever vapers. Analyses controlled for demographic characteristics, use of cannabis and alcohol, and survey date.
resultsEach additional puff year increased the rate ratio (RR) of respiratory symptoms by a factor of 11.36 (95% CI: 4.61-28.00; p<0.001) for never smokers, but among current daily smokers higher pack-equivalent years were not associated with more respiratory symptoms (RR=0.83; 95% CI: 0.23-3.11). Among current vapers, those using pod-style devices were more likely to have more respiratory symptoms (RR=1.25; 95% CI: 1.08-1.45) after adjusting for dose.
conclusionsVaping is associated with an increased risk of reporting respiratory symptoms among never smoking youth and non-daily ever cigarette smokers. Use of e-cigarettes among non-smokers should be discouraged.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.