Evidence map›Paper›PMID 36721772›Full record

ArticleIJID regions2023

The disproportionate case-fatality ratio of COVID-19 between countries with the highest vaccination rates and the rest of the world.

Najmul Haider, Mohammad Nayeem Hasan, Javier Guitian, Rumi A Khan, David McCoy, Francine Ntoumi, Osman Dar, Rashid Ansumana, Md Jamal Uddin, Alimuddin Zumla and 1 more

Abstract read
In one paragraph

Article in IJID regions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. BMJ open · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Najmul HaiderThe Royal Veterinary College, University of London, Hatfield, UK.
Mohammad Nayeem HasanDepartment of Statistics, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Javier GuitianThe Royal Veterinary College, University of London, Hatfield, UK.
Rumi A KhanDivision of Pulmonary Critical Care Medicine, Dell Medical School at University of Texas, Austin, Texas, USA.
David McCoyInstitute of Population Health Sciences, Barts and London Medical and Dental School, Queen Mary University of London, London, UK.
Francine NtoumiCongolese Foundation for Medical Research, Brazzaville, Republic of Congo.
Osman DarChatham House Centre for Global Health Security, Royal Institute of International Affairs, London, UK.
Rashid AnsumanaSchool of Community Health Science, Njala University, Bo, Sierra Leone.
Md Jamal UddinDepartment of Statistics, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Alimuddin ZumlaDivision of Infection and Immunity, Centre for Clinical Microbiology, University College London, London, UK.
Richard A KockThe Royal Veterinary College, University of London, Hatfield, UK.

Funding

Medical Research Council MR/V028561/1
6 · The paper itself

Abstract

Objectives: The global reported cumulative case-fatality ratios (rCFRs) and excess mortality rates of the 20 countries with the highest coronavirus disease 2019 (COVID-19) vaccination rates, the rest of the world and Sub-Saharan Africa (SSA) were compared before and after the commencement of vaccination programmes. Methods: A time series model was used to understand the trend of rCFR over time, and a generalized linear mixed model was used to understand the effect of vaccination on rCFR. Results: By 31 December 2022, an average of 260.3 doses of COVID-19 vaccine per 100 population had been administered in the top 20 vaccinated countries, compared with 152.1 doses in the rest of the world and 51.2 doses in SSA. The mean rCFR of COVID-19 had decreased by 69.0% in the top 20 vaccinated countries, 26.5% in the rest of the world and 7.6% in SSA. Excess mortality had decreased by 48.7% in the top 20 vaccinated countries, compared with 62.5% in the rest of the world and 60.7% in SSA. In a generalized linear mixed model, the reported number of vaccine doses administered (/100 population) (odds ratio 0.64) was associated with a steeper reduction in COVID-19 rCFR. Conclusions: Vaccine equity and faster roll-out across the world is critically important in reducing COVID-19 transmission and CFR.

Indexed as

Case–fatality ratioCOVID-19SARS-CoV-2Vaccine equityVaccine roll outVariants of concern

Identifiers

PMID36721772
PMCPMC9881127

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.