Evidence map›Paper›PMID 36721708›Full record

ArticleCureus2023

Hemophagocytic Lymphohistiocytosis Following COVID-19 Infection.

Guarina Molina, Rafael Contreras, Kyle Coombes, Thilini Walgamage, Maria A Perozo, Martha T DesBiens

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Guarina MolinaInternal Medicine, Danbury Hospital, Danbury, USA.
Rafael ContrerasInternal Medicine, Danbury Hospital, Danbury, USA.
Kyle CoombesSchool of Medicine, American University of the Caribbean, Cupecoy, SXM.
Thilini WalgamageInternal Medicine, Danbury Hospital, Danbury, USA.
Maria A PerozoInternal Medicine, Danbury Hospital, Danbury, USA.
Martha T DesBiensInfectious Disease, Danbury Hospital, Danbury, USA.
Danbury Hospital · USAmerican University of the Caribbean School of Medicine · SX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with multiple inflammatory symptoms involving several organ systems, including hematologic manifestations. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome caused by excessive inflammation in the absence of immune regulation. We present the case of a patient with HLH secondary to dysregulated inflammatory response following COVID-19; we also describe the diagnostic and management challenges associated with the condition.

Indexed as

covid 19disseminated intravascular coagulation (dic)hemophagocytic lymphohistiocytosis (hlh)inflammatory mediatorspancytopeniasoluble interleukin receptors

Identifiers

PMID36721708
PMCPMC9884115
OpenAlexW4318348089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.