Evidence map›Paper›PMID 36721385›Full record

ArticlePulmonary circulation2023

Reduced circulating BMP9 and pBMP10 in hospitalized COVID-19 patients.

Benjamin J Dunmore, Paul D Upton, Kate Auckland, Romit J Samanta, CITIID‐NIHR BioResource COVID‐19 Collaboration, EpiCov Database, Paul A Lyons, Kenneth G C Smith, Stefan Gräf, Charlotte Summers and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Benjamin J DunmoreHeart and Lung Research Institute University of Cambridge Cambridge UK.
Paul D UptonHeart and Lung Research Institute University of Cambridge Cambridge UK.
Kate AucklandHeart and Lung Research Institute University of Cambridge Cambridge UK.
Romit J SamantaHeart and Lung Research Institute University of Cambridge Cambridge UK.
CITIID‐NIHR BioResource COVID‐19 Collaboration
EpiCov Database
Paul A LyonsDepartment of Medicine University of Cambridge School of Clinical Medicine Cambridge UK.
Kenneth G C SmithDepartment of Medicine University of Cambridge School of Clinical Medicine Cambridge UK.
Stefan GräfHeart and Lung Research Institute University of Cambridge Cambridge UK.
Charlotte SummersHeart and Lung Research Institute University of Cambridge Cambridge UK.
Nicholas W MorrellHeart and Lung Research Institute University of Cambridge Cambridge UK.
University of Cambridge · GB

Funding

British Heart Foundation CH/09/001/25945British Heart Foundation RG/19/3/34265Medical Research Council MR/P502091/1
6 · The paper itself

Abstract

Similar to other causes of acute respiratory distress syndrome, coronavirus disease 2019 (COVID-19) is characterized by the aberrant expression of vascular injury biomarkers. We present the first report that circulating plasma bone morphogenetic proteins (BMPs), BMP9 and pBMP10, involved in vascular protection, are reduced in hospitalized patients with COVID-19.

Indexed as

BMPsendothelial cell dysfunctionviral infections and pathogenesis

Identifiers

PMID36721385
PMCPMC9881210
OpenAlexW4317373149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.