Evidence map›Paper›PMID 36721272›Full record

SynthesisHealth and quality of life outcomes2023

Association between overweight, obesity, and quality of life of patients receiving an anticancer treatment for prostate cancer: a systematic literature review.

Léonard Depotte, Maryline Caroux, Joseph Gligorov, Florence Canouï-Poitrine, Yazid Belkacemi, Alexandre De La Taille, Christophe Tournigand, Emmanuelle Kempf

Abstract readSystematic Review
In one paragraph

Synthesis in Health and quality of life outcomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Léonard DepotteAssistance Publique - Hôpitaux de Paris, Department of Medical Oncology, Henri Mondor Teaching Hospital, 1 Rue Gustave Eiffel, 94010, Créteil Cedex, France.
Maryline CarouxDepartment of Medical Oncology, Arras Hospital, Arras, France.
Joseph GligorovAssistance Publique - Hôpitaux de Paris, Department of Medical Oncology, Tenon Teaching Hospital, Paris, France.
Florence Canouï-PoitrineAssistance Publique - Hôpitaux de Paris, NSERM U955, IMRB-CEpiA Team, Henri Mondor Teaching Hospital, Créteil, France.
Yazid BelkacemiAssistance Publique - Hôpitaux de Paris, Department of Radiation Therapy, Henri Mondor and Albert Chenevier Teaching Hospital, Créteil, France.
Alexandre De La TailleAssistance Publique - Hôpitaux de Paris, Department of Urology, Henri Mondor and Albert Chenevier Teaching Hospital, Créteil, France.
Christophe TournigandAssistance Publique - Hôpitaux de Paris, Department of Medical Oncology, Henri Mondor Teaching Hospital, 1 Rue Gustave Eiffel, 94010, Créteil Cedex, France.
Emmanuelle KempfAssistance Publique - Hôpitaux de Paris, Department of Medical Oncology, Henri Mondor Teaching Hospital, 1 Rue Gustave Eiffel, 94010, Créteil Cedex, France. emmanuelle.kempf@aphp.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProstate cancer (PCa) and obesity are two ever-increasing public health issues that can independently impair the quality of life (QOL) of affected patients. Our objective was to evaluate the impact of overweight and obesity on the QOL of patients with PCa receiving an anticancer treatment.

methodsWe performed a systematic review of the literature using PubMed, Embase, Cochrane Library and Web of Science databases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The search equation targeted studies that included PCa patients who had a body mass index (BMI) greater than 25 kg/m

resultsOf 759 identified articles, we selected 20 studies published between 2000 and 2019 of 12,529 patients treated for PCa, including 5549 overweight or obese patients. QOL assessment was performed using nine validated scales and two non-validated questionnaires. Of seven studies on radiotherapy, six found obesity to have a negative impact on patients' QOL (especially urinary, sexual, and bowel-related QOL). Thirteen studies assessed the QOL of patients who underwent radical prostatectomy, with a BMI > 25 kg/m

conclusionBased on the published data, the level of evidence for an association between QOL and overweight or obesity in patients treated for PCa is not high. Prospective cohort studies including this type of patient population are warranted to answer this topical public health issue.

Indexed as

OverweightProstatic NeoplasmsHumansMaleObesityProspective StudiesQuality of LifeHealth-related quality of lifeObesityProstatectomyProstatic NeoplasmsRadiotherapy

Identifiers

PMID36721272
PMCPMC9887848

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.