Evidence map›Paper›PMID 36721188›Full record

SynthesisJournal of orthopaedic surgery and research2023

One in five patients require conversion to arthroplasty after non-vascularized bone grafts in patients with osteonecrosis of the femoral head: a systematic review.

Jianxiong Li, Liang Mo, Guowen Bai, Zhangzheng Wang, Hua Zhang, Jie Li

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Navigating osteonecrosis of the femoral head: from diagnosis to innovative treatment techniques.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jianxiong Li *Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Liang Mo *Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Guowen BaiGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Zhangzheng WangGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Hua ZhangThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China. zhh522@126.com.
Jie LiThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China. lijzzz@163.com.
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CN

Funding

Guangzhou Municipal Science and Technology Bureau 202102020930Traditional Chinese Medicine Bureau of Guangdong Province 20221129Traditional Chinese Medicine Bureau of Guangdong Province 20221136
6 · The paper itself

Abstract

backgroundNon-vascularized bone grafting (NVBG) has demonstrated to treat osteonecrosis of the femoral head (ONFH). There are a number of articles updating the use of NVBG to treat the ONFH, but the percentage of patients subsequently undergoing a total hip arthroplasty (THA) is controversial.

methodsSeveral electronic databases, including PubMed, Embase, Web of Science, and Cochrane databases, were searched to find studies using NVBG to treat ONFH. The pooled rate and 95% confidence interval (CI) were used to assess the conversion rate to THA after NVBG. In addition, we performed subgroup, sensitivity, and publication bias analysis.

resultsA total of 37 studies describing 2599 hips were included. The mean weighted follow-up time was 50.5 months and the mean age at surgery was 36.3 years. The conversion rate to THA after NVBG was 21% (95%CI: 17% to 25%), and subgroup analyzes indicated lightbulb, trapdoor and Phemister techniques incidences with THA of 15%, 19%, and 24%, respectively.

conclusionsThis study preliminarily obtained the general trend of the survival rate of NVBG patients, but these results should be interpreted cautiously. Pooled results from 2599 hips and of these nearly 80% with early stage of osteonecrosis, showed that approximately 21% of patients underwent a THA following NVBG. NVBG treatment for patient with ONFH appears to defer or at least delay the need for THA.

Indexed as

Arthroplasty, Replacement, HipFemur Head NecrosisAdultDatabases, FactualFemur HeadHumansHip preservationMeta-analysisNon-vascularized bone graftOsteonecrosis of the femoral headTotal hip arthroplasty

Identifiers

PMID36721188
PMCPMC9887751
OpenAlexW4318612767

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.