Evidence map›Paper›PMID 36721052›Full record

ArticleEye (London, England)2023

Are PHOMS a clinical sign of optic neuritis?

Ahmed Aziria, Manon Philibert, Romain Deschamps, Catherine Vignal, Rabih Hage

Abstract readComment
In one paragraph

Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ahmed AziriaRothschild Foundation Hospital, department of Neuro-Ophthalmology, 29 rue Manin, 75940, Paris, Cedex 19, France. ahmed.aziria@hotmail.com.ORCID 0000-0002-5133-2553
Manon PhilibertRothschild Foundation Hospital, department of Neuro-Ophthalmology, 29 rue Manin, 75940, Paris, Cedex 19, France.
Romain DeschampsRothschild Foundation Hospital, department of neurology, 29 rue Manin, 75940, Paris, Cedex 19, France.
Catherine VignalRothschild Foundation Hospital, department of Neuro-Ophthalmology, 29 rue Manin, 75940, Paris, Cedex 19, France.ORCID 0000-0003-0292-8905
Rabih HageRothschild Foundation Hospital, department of Neuro-Ophthalmology, 29 rue Manin, 75940, Paris, Cedex 19, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAssess the prevalence and evolution of PHOMS in optic neuritis.

methodsWe analysed the medical files of 126 patients included in the OCTON cohort. Patients' medical files, digital retinal images and OCT examinations were reviewed, searching for optic nerve head oedema and PHOMS at the initial presentation and during the follow-up.

resultsWe included 102 patients in the final analysis. Twenty-nine (29) eyes had optic nerve head oedema at the initial presentation. PHOMS were found to be present in 8 eyes affected with optic neuritis. All cases of PHOMS were associated with optic nerve head oedema. All the PHOMS decreased in size and disappeared with the improvement of the oedema. DISCUSSION: Our results show that PHOMS is not a common sign of optic neuritis. We didn't observe any case of PHOMS in the absence of optic nerve head oedema in eyes with optic neuritis. PHOMS seem to be a rare sign of optic neuritis associated to optic nerve head oedema, and they tend to disappear with the improvement of the optic nerve head oedema. We suggest that the presence of PHOMS in optic neuritis eyes with no optic nerve oedema should be a considered warning sign.

Indexed as

Optic NeuritisPapilledemaHumansOptic NerveRetinal Ganglion CellsTomography, Optical Coherence

Identifiers

PMID36721052
PMCPMC10482841

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