Evidence map›Paper›PMID 36721030›Full record

ArticleCommunications biology2023

Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection.

Wei-Jiun Tsai, Yi-Hsin Lai, Yong-An Shi, Michal Hammel, Anthony P Duff, Andrew E Whitten, Karyn L Wilde, Chun-Ming Wu, Robert Knott, U-Ser Jeng and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Transcriptome of macrolide-resistantMicrobiology resource announcements · 2025
    Article
  3. The burden of group AiScience · 2025
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 4 countries.

Wei-Jiun TsaiInstitute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yi-Hsin Lai *Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yong-An Shi *Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Michal HammelMolecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0002-5610-9289
Anthony P DuffAustralian Nuclear Science and Technology Organisation, Lucas Heights, NSW, Australia.
Andrew E WhittenAustralian Nuclear Science and Technology Organisation, Lucas Heights, NSW, Australia.ORCID 0000-0001-8856-3120
Karyn L WildeAustralian Nuclear Science and Technology Organisation, Lucas Heights, NSW, Australia.ORCID 0000-0002-0538-6796
Chun-Ming WuNational Synchrotron Radiation Research Center, Hsinchu Science Park, Hsinchu, Taiwan.
Robert KnottAustralian Nuclear Science and Technology Organisation, Lucas Heights, NSW, Australia.
U-Ser JengNational Synchrotron Radiation Research Center, Hsinchu Science Park, Hsinchu, Taiwan.
Chia-Yu KangDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chih-Yu HsuDepartment of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Medical College, Tainan, Taiwan.
Jian-Li WuInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Pei-Jane TsaiInstitute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chuan Chiang-NiGraduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0002-0753-035X
Jiunn-Jong WuDepartment of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.
Yee-Shin LinDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ching-Chuan LiuDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Toshiya SendaStructural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki, Japan.ORCID 0000-0002-5153-928X
Shuying WangInstitute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan. sswang23@mail.ncku.edu.tw.ORCID 0000-0003-3339-8070
National Cheng Kung University · TWAustralian Nuclear Science and Technology Organisation · AUAsia University · TWChang Gung University · TWHigh Energy Accelerator Research Organization · JPLawrence Berkeley National Laboratory · USNational Synchrotron Radiation Research Center · TWNational Tsing Hua University · TW

Funding

User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
NIGMS NIH HHS P30 GM124169
6 · The paper itself

Abstract

Group A Streptococcus (GAS) is a strict human pathogen possessing a unique pathogenic trait that utilizes the cooperative activity of NAD

Indexed as

StreptococcusStreptolysinsAnimalsBacterial ProteinsHumansMiceNAD+ NucleosidaseBacterial ProteinsNAD+ Nucleosidasestreptolysin OStreptolysins

Identifiers

PMID36721030
PMCPMC9887584
OpenAlexW4318754193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.