Evidence map›Paper›PMID 36720883›Full record

ArticleScientific data2023

An RNA-seq time series of the medaka pituitary gland during sexual maturation.

Eirill Ager-Wick, Gersende Maugars, Kristine von Krogh, Romain Fontaine, Finn-Arne Weltzien, Christiaan Henkel

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. MedakaBase as a unified genomic resource platform for medaka fish biology.DNA research : an international journal for rapid publication of reports on genes and genomes · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Eirill Ager-WickPhysiology Unit, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.
Gersende MaugarsPhysiology Unit, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.
Kristine von KroghPhysiology Unit, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.
Romain FontainePhysiology Unit, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.ORCID 0000-0003-1123-9773
Finn-Arne WeltzienPhysiology Unit, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway. finn-arne.weltzien@nmbu.no.ORCID 0000-0002-5111-1558
Christiaan HenkelPhysiology Unit, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway. christiaan.henkel@nmbu.no.ORCID 0000-0001-9838-8215
Norwegian University of Life Sciences · NOStress Environnementaux et Biosurveillance des Milieux Aquatiques · FR

Funding

Norges Forskningsråd (Research Council of Norway) 248828Norges Forskningsråd (Research Council of Norway) 251307Norges Forskningsråd (Research Council of Norway) 255601
6 · The paper itself

Abstract

Directing both organismal homeostasis and physiological adaptation, the pituitary is a key endocrine gland in all vertebrates. One of its major tasks is to coordinate sexual maturation through the production and release of hormones stimulating gonad development. In order to study its developmental dynamics in the model fish medaka (Oryzias latipes), we sampled both the pituitary and the ovaries of 68 female fish. Of these, 55 spanned the entire course of sexual maturation from prepubertal juveniles to spawning adults. An additional 13 showed either considerably faster or slower growth and development than the majority of fish. We used histological examination of the ovaries to determine a histological maturation stage, and analyzed the pituitary glands using RNA-seq optimized for low input. Taken together, these data reveal the timing of hormone production priorities, and form a comprehensive resource for the study of their regulation.

Indexed as

OryziasRNA-SeqAnimalsFemalePituitary GlandSexual MaturationTime Factors

Identifiers

PMID36720883
PMCPMC9889309
OpenAlexW4318706856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.