Evidence map›Paper›PMID 36720843›Full record

ArticlePsychogeriatrics : the official journal of the Japanese Psychogeriatric Society2023

Sedatives and analgesics are major contributors to potentially inappropriate duplicate prescriptions in geriatric psychiatry.

Martin Schulze Westhoff, Sebastian Schröder, Adrian Groh, Helge Frieling, Stefan Bleich, Felix Koop, Dirk O Stichtenoth, Benjamin Krichevsky, Johannes Heck

Open access · hybridAbstract read
In one paragraph

Article in Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Martin Schulze WesthoffDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0003-3262-8137
Sebastian SchröderDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0003-0905-274X
Adrian GrohDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0002-4407-3557
Helge FrielingDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-5146-9720
Stefan BleichDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-5004-3824
Felix KoopInstitute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-7378-7877
Dirk O StichtenothInstitute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0002-6526-0917
Benjamin KrichevskyInstitute for General Practice and Palliative Care, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-5899-0113
Johannes HeckInstitute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0002-5382-3014
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in elderly psychiatric inpatients using a novel categorisation of DPs that differentiates between appropriate duplicate prescriptions (ADPs) and potentially inappropriate duplicate prescriptions (PIDPs).

methodsThe study was conducted as a monocentric retrospective cross-sectional pilot study on the gerontopsychiatric ward of the Department of Psychiatry, Social Psychiatry and Psychotherapy of Hannover Medical School, a large university hospital in northern Germany. The outcome measures were the nature and frequency of PIDPs compared with the frequency of ADPs.

resultsFor 92 individual patients a total of 339 medication chart reviews were conducted between April 2021 and February 2022. The median age of the study population was 73 years (interquartile range (IQR) 68-82 years); 64.6% were female. Patients' medications comprised a median of eight drugs (IQR 6-11 drugs) and 43.1% of the study population were exposed to at least one PIDP (at least one grade-1 PIDP: 39.5%; at least one grade-2 PIDP: 5.0%; at least one grade-3 PIDP: 1.5%). Sedatives were most frequently responsible for grade-1 and grade-2 PIDPs, while grade-3 PIDPs were elicited exclusively by analgesics. Nearly half of the study population (49.0%) displayed at least one ADP.

conclusionEven though the clinical implications of PIDPs are not fully established to date, we recommend that physicians who treat elderly psychiatric patients pay special attention to PIDPs, especially PIDPs elicited by sedatives. Termination of PIDPs may prevent adverse drug reactions and save healthcare expenditures.

Indexed as

Geriatric PsychiatryHypnotics and SedativesAgedAged, 80 and overAnalgesicsCross-Sectional StudiesDrug PrescriptionsFemaleHumansMalePilot ProjectsPrescriptionsRetrospective StudiesAnalgesicsHypnotics and Sedativesduplicate prescriptionsgeriatric psychiatrymedication reviewpharmacotherapy safety

Identifiers

PMID36720843
PMCPMC11578029
OpenAlexW4318754200

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.