Evidence map›Paper›PMID 36720753›Full record

ReviewCurrent allergy and asthma reports2023

C-Type Lectin Receptor Mediated Modulation of T2 Immune Responses to Allergens.

Alba Angelina, Leticia Martín-Cruz, Andrés de la Rocha-Muñoz, Begoña Lavín-Plaza, Oscar Palomares

Open access · hybridAbstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Ameliorative effects ofThe journal of allergy and clinical immunology. Global · 2026
    Article
  3. Review
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  14. Role of Small Molecule Ligands in IgE-Mediated Allergy.Current allergy and asthma reports · 2023
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alba Angelina *Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Avenida Complutense S/N, Madrid, 28040, Spain.
Leticia Martín-Cruz *Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Avenida Complutense S/N, Madrid, 28040, Spain.
Andrés de la Rocha-MuñozDepartment of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Avenida Complutense S/N, Madrid, 28040, Spain.
Begoña Lavín-PlazaDepartment of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Avenida Complutense S/N, Madrid, 28040, Spain.
Oscar PalomaresDepartment of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Avenida Complutense S/N, Madrid, 28040, Spain. oscar.palomares@quim.ucm.es.
Universidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAllergic diseases represent a major health problem of increasing prevalence worldwide. In allergy, dendritic cells (DCs) contribute to both the pathophysiology and the induction of healthy immune responses to the allergens. Different studies have reported that some common allergens contain glycans in their structure. C-type lectin receptors (CLRs) expressed by DCs recognize carbohydrate structures and are crucial in allergen uptake, presentation, and polarization of T cell responses. This review summarizes the recent literature regarding the role of CLRs in the regulation of type 2 immune responses to allergens. RECENT

findingsIn this review, we highlight the capacity of CLRs to recognize carbohydrates in common allergens triggering different signaling pathways involved in the polarization of CD4

Indexed as

AllergensHypersensitivityDesensitization, ImmunologicHumansImmune ToleranceImmunityLectins, C-TypeMannansAllergensLectins, C-TypeMannansAllergensAllergen-specific immunotherapy (AIT)AllergyC-type lectin receptors (CLRs)MannanType-2 immune responses

Identifiers

PMID36720753
PMCPMC9985561
OpenAlexW4318755290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.