Evidence map›Paper›PMID 36720750›Full record

ArticleNeuroradiology2023

Detection of cerebral cortical vein thrombosis with high-resolution susceptibility weighted imaging -  A comparison with MR venography and standard MR sequences.

Faiza Boukerche, Sivasubramanian Balakrishnan, Paul Kalapos, Krishnamoorthy Thamburaj

Open access · bronzeAbstract read
In one paragraph

Article in Neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Faiza BoukerchePreliminary Year General Surgery, UCSF East Bay, University of California Irvine, Irvine, CA, 92697, USA.
Sivasubramanian BalakrishnanHitech Scans, Coimbatore, 641012, India.
Paul KalaposDepartment of Radiology, Penn State Health Milton Hershey Medical Center, Hershey, PA, 17033, USA.
Krishnamoorthy ThamburajDepartment of Radiology, Penn State Health Milton Hershey Medical Center, Hershey, PA, 17033, USA. kthamburaj1@outlook.com.ORCID http://orcid.org/0000-0002-6488-2861
Penn State Milton S. Hershey Medical Center · USOrthopaedic Research Group · INUniversity of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeComparison of the performance of high-resolution susceptibility weighted imaging with standard MR sequences and MR venography to identify cortical vein clots.

methodsA retrospective review of 51 consecutive cases of cerebral venous thrombosis and 27 controls was performed with independent analysis of all MR sequences. Reference standard was obtained with consensus in a separate session by reviewing all MR sequences together.

resultsCortical vein clots were observed in 30 cases including 9 males and 21 females in the age range of 1 month to 70 years (Mean 34.9 ± 20.2 years). Sensitivity, specificity, negative predictive value, positive predictive value and accuracy of susceptibility weighted imaging for the identification of cortical vein clots were 0.93, 1.0, 1.0, 0.96 and 0.97 respectively. For all other sequences, sensitivity ranged from 0.06 to 0.39 and accuracy from 0.60 to 0.73. Combination of all sequences yielded a value of 1.0 for sensitivity, specificity, positive predictive value, negative predictive value and accuracy for the detection of cortical vein clots. Significant result for area under the receiver operating curve was observed only for SWI with a value of 0.91 (p - .000).

conclusionSusceptibility weighted imaging demonstrates the best sensitivity and accuracy among standard MR sequences including MR venography for the detection of early stage cortical vein clots. However, it needs to be interpreted in combination with other MR sequences for the most accurate evaluation of cortical vein clots.

Indexed as

Intracranial ThrombosisThrombosisCranial SinusesFemaleHumansInfantMagnetic Resonance ImagingMalePhlebographySensitivity and SpecificityCerebral venous sinus thrombosisCerebral venous thrombosisCortical vein thrombosisCortical venous thrombosisSWI

Identifiers

PMID36720750
PMCPMC9889237
OpenAlexW4318676786

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.