Evidence map›Paper›PMID 36720270›Full record

ArticleNature medicine2023

Determinants of COVID-19 vaccination status and hesitancy among older adults in China.

Gewei Wang, Yao Yao, Yafeng Wang, Jinquan Gong, Qinqin Meng, Hui Wang, Wenjin Wang, Xinxin Chen, Yaohui Zhao

Open access · bronzeAbstract read
In one paragraph

Article in Nature medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
32.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Gewei Wang *Institute of Social Science Survey, Peking University, Beijing, China.
Yao Yao *China Center for Health Development Studies, Peking University, Beijing, China.
Yafeng Wang *Institute of Social Science Survey, Peking University, Beijing, China.
Jinquan GongInstitute of Social Science Survey, Peking University, Beijing, China.
Qinqin MengInstitute of Social Science Survey, Peking University, Beijing, China.
Hui WangChina Center for Economic Research, National School of Development, Peking University, Beijing, China.
Wenjin WangChina Center for Economic Research, National School of Development, Peking University, Beijing, China.
Xinxin ChenInstitute of Social Science Survey, Peking University, Beijing, China. xinxinchen@pku.edu.cn.ORCID http://orcid.org/0000-0002-9597-8524
Yaohui ZhaoChina Center for Economic Research, National School of Development, Peking University, Beijing, China. yhzhao@nsd.pku.edu.cn.ORCID http://orcid.org/0000-0002-9252-9715
Peking University · CN

Funding

China Health and Retirement Longitudinal StudyR01AG037031 · NIA · PEKING UNIVERSITY · PI STRAUSS, JOHN A, WANG, YAFENG · 2010 to 2024
$15.1M
Influences of Early and Later Life Events on Cognition and All-Cause Dementia in ChinaR01AG067625 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI STRAUSS, JOHN A · 2019 to 2024
$2.7M
Harmonized Cognitive and Dementia Assessment in ChinaR01AG053228 · NIA · PEKING UNIVERSITY · PI HUANG, YUEQIN, STRAUSS, JOHN A · 2016 to 2019
$1.7M
NIA NIH HHS R01 AG037031NIA NIH HHS R01 AG053228NIA NIH HHS R01 AG067625
6 · The paper itself

Abstract

Vaccination is the primary defense against severe acute respiratory syndrome coronavirus 2, especially among older adults and those with chronic conditions. Using a nationally representative sample of 12,900 participants from the fifth wave (2021-2022) of the China Health and Retirement Longitudinal Study (CHARLS), we examined the coronavirus disease 2019 (COVID-19) vaccination status and the determinants of vaccination hesitancy in Chinese adults aged 52 and older. By July/August 2022, 92.3% of the Chinese population aged 60 years and older had received at least one COVID-19 vaccination, 88.6% had completed the primary series and 72.4% had received a booster. Those aged 80 years and older had lower vaccination rates, with 71.9% and 46.7% completing the primary series and booster shots, respectively. These statistics represent the situation before China ended the Zero-COVID policy in November 2022 because vaccination stagnated between July/August and November 2022. Multivariate regression analysis revealed that belonging to the oldest age groups (individuals aged 70 years and older and especially those aged 80 years and older) as well as being female and unmarried, residing in urban areas, being functionally dependent and having chronic conditions meant that these individuals were less likely to receive COVID-19 vaccines. Our regression analysis results were corroborated by self-reported reasons for nonvaccination. Vaccination hesitancy probably contributed to excessive mortality among vulnerable populations after China ceased its Zero-COVID policy. Our study provides important lessons on how to balance containment efforts with vaccination and treatment measures, as well as highlighting the need to clarify the side effects and contraindications of vaccines early on.

Indexed as

COVID-19AgedAged, 80 and overChinaCOVID-19 VaccinesFemaleHumansLongitudinal StudiesMaleMiddle AgedSARS-CoV-2VaccinationCOVID-19 Vaccines

Identifiers

PMID36720270
PMCPMC10285745
OpenAlexW4318711566

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.