Evidence map›Paper›PMID 36719724›Full record

ArticleeLife2023

Alexandro Landshammer, Adriano Bolondi, Helene Kretzmer, Christian Much, René Buschow, Alina Rose, Hua-Jun Wu, Sebastian D Mackowiak, Bjoern Braendl, Pay Giesselmann and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 3 countries.

Alexandro Landshammer *Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.ORCID https://orcid.org/0000-0001-5367-3303
Adriano Bolondi *Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.ORCID https://orcid.org/0000-0002-1096-9435
Helene KretzmerDepartment of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Christian MuchDepartment of Biochemistry, University of Colorado Boulder and BioFrontiers Institute, Boulder, United States.
René BuschowMax Planck Institute for Molecular Genetics, Microscopy Core Facility, Berlin, Germany.ORCID https://orcid.org/0000-0002-9800-2578
Alina RoseHelmholtz Institute for Metabolic, Obesity and Vascular Research, Leipzig, Germany.
Hua-Jun WuDepartment of Data Science, Dana-Farber Cancer Institute, Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, United States.
Sebastian D MackowiakDepartment of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.ORCID https://orcid.org/0000-0003-1673-5389
Bjoern BraendlDepartment of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Pay GiesselmannDepartment of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Rosaria TornisielloDepartment of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Krishna Mohan ParsiProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, United States.ORCID https://orcid.org/0000-0002-6002-3816
Jack HueyProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, United States.
Thorsten MielkeMax Planck Institute for Molecular Genetics, Microscopy Core Facility, Berlin, Germany.
David MeierhoferMax Planck Institute for Molecular Genetics, Mass Spectrometry Core Facility, Berlin, Germany.
René MaehrCenter for Precision Medicine Multi-Omics Research, School of Basic Medical Sciences, Peking University Health Science Center and Peking University Cancer Hospital and Institute, Beijing, China.ORCID https://orcid.org/0000-0002-9520-3382
Denes HniszDepartment of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Franziska MichorDepartment of Stem Cell and Regenerative Biology, Harvard University, Cambridge, United States.
John L RinnDepartment of Biochemistry, University of Colorado Boulder and BioFrontiers Institute, Boulder, United States.ORCID https://orcid.org/0000-0002-7231-7539
Alexander MeissnerDepartment of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.ORCID https://orcid.org/0000-0001-8646-7469
Max Planck Institute for Molecular Genetics · DEBroad Institute · USKing University · USUniversity of Colorado Boulder · USUniversity of Massachusetts Chan Medical School · US

Funding

Regulatory Roles and Dynamics of Nuclear long-noncoding RNAs in PluripotencyP01GM099117 · NIGMS · HARVARD UNIVERSITY · PI MEISSNER, ALEXANDER · 2011 to 2021
$21.2M
NIGMS NIH HHS P01 GM099117NIH HHS DP3K111898NIH HHS P01GM099117
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have emerged as fundamental regulators in various biological processes, including embryonic development and cellular differentiation. Despite much progress over the past decade, the genome-wide annotation of lncRNAs remains incomplete and many known non-coding loci are still poorly characterized. Here, we report the discovery of a previously unannotated lncRNA that is transcribed 230 kb upstream of the

Indexed as

RNA, Long NoncodingCell DifferentiationEndodermEpithelial-Mesenchymal TransitionFemaleGene Expression Regulation, DevelopmentalHumansPregnancySOXF Transcription FactorsRNA, Long NoncodingSOXF Transcription Factorscell biologyendodermenhancergeneticsgenomicshumanlncRNAsSOX17

Identifiers

PMID36719724
PMCPMC9889090
OpenAlexW4318619312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.