ArticleResearch on child and adolescent psychopathology2023
Aging and Pubertal Development Differentially Predict Symptoms of ADHD, Depression, and Impairment in Children and Adolescents: An Eight-Year Longitudinal Study.
Article in Research on child and adolescent psychopathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Rates of Depression in Children and Adolescents With ADHD: A Systematic Review and Meta-Analysis.Journal of attention disorders · 2025Pooled it
- ADHD and Sex Hormones in Females: A Systematic Review.Journal of attention disorders · 2025Pooled it
- Sex differences in children and adolescents with attention-deficit/hyperactivity disorder: a literature review.Frontiers in child and adolescent psychiatry · 2025Pooled it
- Cognitive Disengagement Syndrome: Changes in Severity, Comorbid Conditions, and Impairment from Childhood to Adolescence.Research on child and adolescent psychopathology · 2026Article
- ADHD and the female reproductive stages: menstruation, perinatal and menopause.Archives of women's mental health · 2026Article
- Indirect associations between adolescent ADHD and/or oppositional defiant disorder symptoms and adult incomes: the mediating roles of education and co-occurring psychiatric disorders.European child & adolescent psychiatry · 2026Article
- Observational
- A Review of Sex and Gender Factors in Stimulant Treatment for ADHD: Knowledge Gaps and Future Directions.Journal of attention disorders · 2025Review
- Prediction of internalizing and externalizing symptoms in late childhood from attention-deficit/hyperactivity disorder symptoms in early childhood.Development and psychopathology · 2025Article
- Explainable Artificial Intelligence for Predicting Attention Deficit Hyperactivity Disorder in Children and Adults.Healthcare (Basel, Switzerland) · 2025Article
- Research advances and future directions in female ADHD: the lifelong interplay of hormonal fluctuations with mood, cognition, and disease.Frontiers in global women's health · 2025Review
- Coming of age in war: Early life adversity, age at menarche, and mental health.Psychoneuroendocrinology · 2024Review
- Pubertal timing in adolescents with ADHD: extension and replication in an all-female sample.European child & adolescent psychiatry · 2024Article
- Attention-deficit/hyperactivity disorder and the menstrual cycle: Theory and evidence.Hormones and behavior · 2024Review
- N-Acetylcysteine Alleviates Depressive-Like Behaviors in Adolescent EAAC1International journal of biological sciences · 2024Article
- Earlier pubertal timing, not tempo, links time-limited early adversity with psychopathology.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
Activational effects of the reproductive neuroendocrine system may explain why some youths with ADHD are at greater risk for exacerbated ADHD symptoms (hyperactivity, inattention, impulsivity) during adolescence. For youths diagnosed with ADHD, first signs of ADHD symptoms become noticeable by multiple reporters (e.g., teachers, parents) when children enter schools, typically around kindergarten. The current study examined possible sex differences in ADHD, impairment, and comorbidity due to pubertal effects, as the role of pubertal development in ADHD is understudied. ADHD symptoms, depressive symptoms, impairment, and pubertal stage were assessed annually by multiple reporters in a well-characterized community sample of 849 children over-recruited for ADHD over eight years. Ages ranged from 7 to 13 years (38.16% female) at wave 1. Multilevel models indicated that males had higher levels of hyperactivity, impulsivity, and inattention than females, but that females had higher levels of impairment than males. Inattention symptoms did not show marked maturation changes. Hyperactivity and impulsivity declined as youth aged and impairment increased as youth aged. Lastly, depressive symptoms largely increased as youth aged and were higher amongst youth at later pubertal stages. Put together, aging and pubertal development are associated with improved ADHD symptoms but not for youth with high impairment. Findings from this study contributes to understanding the role that aging, pubertal status, and pubertal development plays in ADHD, impairment, and comorbidity in children and adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.