Evidence map›Paper›PMID 36719470›Full record

ArticleApoptosis : an international journal on programmed cell death2023

CXCR4 enhances the inhibitory effects of bone mesenchymal stem cells on lung cell apoptosis in a rat model of smoking-induced COPD.

Jiansheng Gao, Yuli Liang, Jiabao Chen, Huihui Shen, Hua Liu

Open access · bronzeAbstract read
In one paragraph

Article in Apoptosis : an international journal on programmed cell death, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiansheng GaoFirst Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Yuli LiangFirst Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Jiabao ChenFirst Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Huihui ShenFirst Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.
Hua LiuFirst Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China. liuhuagy63@163.com.
First Affiliated Hospital of Guangdong Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic obstructive pulmonary disease is the 3rd leading cause of death worldwide, and the available treatments are unsatisfactory, resulting in a major economic burden. As cellular therapy is commonly used for lung disease, we investigated a treatment with CXCR4-overexpressing BMSCs in a COPD model. We extracted and purified Bone marrow mesenchymal stem cells (BMSCs) from SD rats. COPD apoptosis model was established by cigarette smoke exposure. BMSCs (1 × 10

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationPulmonary Disease, Chronic ObstructiveAnimalsApoptosisBone Marrow CellsLungRatsRats, Sprague-DawleyReceptors, CXCR4SmokingCxcr4 protein, ratReceptors, CXCR4Anti-apoptosisBone marrow mesenchymal stem cellsChronic obstructive pulmonary diseaseCXCR4

Identifiers

PMID36719470
PMCPMC9888343
OpenAlexW4318619286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.