Evidence map›Paper›PMID 36719466›Full record

ReviewImmunogenetics2023

Innate receptors modulating adaptive T cell responses: KIR-HLA interactions and T cell-mediated control of chronic viral infections.

Laura Mora-Bitria, Becca Asquith

Open access · hybridAbstract readReview
In one paragraph

Review in Immunogenetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Modelling HIV-1 control and remission.NPJ systems biology and applications · 2024
    Review
  5. Article
  6. Review
  7. The implication of infection with respiratory syncytial virus in pediatric recurrent wheezing and asthma: knowledge expanded post-COVID-19 era.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Laura Mora-BitriaDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.
Becca AsquithDepartment of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK. b.asquith@imperial.ac.uk.
Imperial College London · GB

Funding

Medical Research Council G1001052Medical Research Council J007439Medical Research Council MR/J007439/1Wellcome Trust 103865Z/14/Z
6 · The paper itself

Abstract

Killer-cell immunoglobulin-like receptors (KIRs) are mainly expressed on natural killer (NK) cells and are key regulators of innate immune responses. NK cells are the first responders in the face of infection and help promote placentation during pregnancy; the importance of KIRs in these NK-mediated processes is well-established. However, mounting evidence suggests that KIRs also have a prominent and long-lasting effect on the adaptive immune system. Here, we review the evidence for the impact of KIRs on T cell responses with a focus on the clinical significance of this interaction.

Indexed as

T-LymphocytesVirus DiseasesFemaleHumansImmunity, InnateKiller Cells, NaturalPregnancyReceptors, KIRReceptors, KIRAICDCD8 + T cellsChronic viral infectionsHLAKIRNK cells

Identifiers

PMID36719466
PMCPMC9887252
OpenAlexW4318591720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.